Nano-Based drug delivery systems for periodontal tissue regeneration

H Chen, Y Zhang, T Yu, G Song, T Xu, T Xin, Y Lin… - Pharmaceutics, 2022 - mdpi.com
Periodontitis is a dysbiotic biofilm-induced and host-mediated inflammatory disease of tooth
supporting tissues that leads to progressive destruction of periodontal ligament and alveolar …

New insight in urological cancer therapy: From epithelial-mesenchymal transition (EMT) to application of nano-biomaterials

P He, Q Dai, X Wu - Environmental Research, 2023 - Elsevier
A high number of cancer-related deaths (up to 90) are due to metastasis and simple
definition of metastasis is new colony formation of tumor cells in a secondary site. In tumor …

Assessment of NLRP3 gene polymorphisms with periodontitis as compared with healthy periodontium in Iraqi Arabs patients

AA Mahmood, RF Abbas - European Journal of Dentistry, 2023 - thieme-connect.com
Objectives The nod-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome
regulates the maturation and release of the cytokines as well as the activation of caspase in …

Ability of gingival crevicular fluid volume, E‐cadherin, and total antioxidant capacity levels for predicting outcomes of nonsurgical periodontal therapy for periodontitis …

HR Hussein, AA Abdulkareem… - Journal of …, 2024 - Wiley Online Library
Objectives To determine the potential of gingival crevicular fluid (GCF) volume, E‐cadherin
and total antioxidant capacity (TAC) levels to predict the outcomes of nonsurgical …

Cytokines secreted by inflamed oral mucosa: implications for oral cancer progression

EB Danella, M Costa de Medeiros, NJ D'Silva - Oncogene, 2023 - nature.com
The oral mucosa has an essential role in protecting against physical, microbial, and
chemical harm. Compromise of this barrier triggers a wound healing response. Key events …

Salivary E‐cadherin as a biomarker for diagnosis and predicting grade of periodontitis

NM Kazem, AA Abdulkareem… - Journal of Periodontal …, 2023 - Wiley Online Library
Objectives To determine the abilities of salivary E‐cadherin to differentiate between
periodontal health and periodontitis and to discriminate grades of periodontitis. Background …

Gingival tissue samples from periodontitis patients demonstrate epithelial–mesenchymal transition phenotype

SS Saliem, SY Bede, AA Abdulkareem… - Journal of …, 2023 - Wiley Online Library
Objective To determine the expression of key epithelial–mesenchymal transition (EMT)
markers in gingival tissue samples collected from patients with periodontitis. Background …

Single‐cell sequencing, spatial transcriptome ad periodontitis: Rethink pathogenesis and classification

S Razzouk - Oral Diseases, 2024 - Wiley Online Library
Objective This narrative review illuminates on the application of single‐cell RNA sequencing
(scRNA‐seq) and spatial transcriptomics (ST) in periodontitis and highlights the probability …

miRNA-199b-5p suppresses of oral squamous cell carcinoma by targeting apical-basolateral polarity via Scribble/Lgl

S Kim, S Park, YJ Kim, J Hyun, J Choi - Molecular Therapy Nucleic Acids, 2024 - cell.com
In epithelial cells, Scribble forms cell-cell junctions and contributes to cell morphology and
homeostasis by regulating apical-basolateral polarity in mammals and functions as a tumor …

Diagnostic Potential of Salivary Interleukin‐1β and IL‐10 for Distinguishing Periodontal Health From Periodontitis and Stable From Unstable Periodontitis: A Case …

ZJ Raheem, HR Abdulbaqi - International Journal of Dentistry, 2024 - Wiley Online Library
Objective: This case–control study aimed to investigate the diagnostic accuracy of salivary
interleukin (IL)‐1β, IL‐10, and IL‐1β/IL‐10 ratio to discriminate periodontitis from periodontal …