I. Executive Summary Background The 5 years since the publication of the first International
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …

Contributing Authors Isam Alobid, MD, PhD1, Nithin D. Adappa, MD2, Henry P. Barham,
MD3, Thiago Bezerra, MD4, Nadieska Caballero, MD5, Eugene G. Chang, MD6, Gaurav …

This systematic review evaluates the efficacy and safety of biologicals for chronic
rhinosinusitis with nasal polyps (CRSwNP) compared with the standard of care. PubMed …

Background Chronic rhinosinusitis (CRS) is based on sinonasal symptoms coupled with
sinonasal tissue inflammation. Establishing the epidemiology and prevalence of CRS …

The accurate diagnosis of rhinologic disease depends on the clinical history, examination
findings and, in many cases, further investigations. There are a wide variety of diagnostic …

Background Chronic rhinosinusitis with nasal polyposis (CRSwNP) negatively affects health‐
related quality of life (HRQoL). In a previously reported randomized clinical trial …

Background With a focus on patient-centered care, there is increasing policy interest in
patient-reported outcome measures (PROMs) to inform improvements in health care …

Objective Both endoscopic sinus surgery (ESS) and biologic therapies have shown
effectiveness for medically‐refractory chronic rhinosinusitis with nasal polyps (CRSwNP) …

Objectives/Hypothesis The goal of the study was to perform a systematic review with meta‐
analysis to determine the mean change in the 22‐item Sino‐Nasal Outcome Test (SNOT …

Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a predominantly type 2‐
mediated inflammatory disease with high symptom burden and reduced health‐related …