The Role of Bezlotoxumab for the Prevention of Recurrent Clostridioides difficile Infections: A Review of the Current Literature and Paradigm Shift after 2021
Clostridioides difficile infections (CDIs), and particularly recurrent infections, cause a
significant burden on the health-care system. Bezlotoxumab is a new agent for the …
significant burden on the health-care system. Bezlotoxumab is a new agent for the …
[HTML][HTML] Fidaxomicin vs vancomycin for the treatment of a first episode of Clostridium difficile infection: a meta-analysis and systematic review
Clostridium difficile infection (CDI) continues to possess a significant disease burden in the
United States (US) as well as all over the world. Given the increase in severity and …
United States (US) as well as all over the world. Given the increase in severity and …
Japanese clinical practice guidelines for management of Clostridioides (Clostridium) difficile infection
H Kunishima, H Ohge, H Suzuki, A Nakamura… - Journal of Infection and …, 2022 - jiac-j.com
Toxigenic culture and cytotoxicity assays are standard tests for detecting C. difficile infection
(CDI). Others include immunochromatographic strips, a rapid diagnostic test that detects …
(CDI). Others include immunochromatographic strips, a rapid diagnostic test that detects …
Clinical complications in patients with primary and recurrent Clostridioides difficile infection: A real-world data analysis
P Feuerstadt, M Boules, L Stong… - SAGE open …, 2021 - journals.sagepub.com
Objective: Clostridioides difficile infection and recurrent C. difficile infection result in
substantial economic burden and healthcare resource use. Sepsis and bowel surgery are …
substantial economic burden and healthcare resource use. Sepsis and bowel surgery are …
Total synthesis of tiacumicin A. Total synthesis, relay synthesis, and degradation studies of fidaxomicin (tiacumicin B, lipiarmycin A3)
H Hattori, E Kaufmann… - The Journal of …, 2018 - ACS Publications
The commercial macrolide antibiotic fidaxomicin was synthesized in a highly convergent
manner. Salient features of this synthesis include a β-selective noviosylation, a β-selective …
manner. Salient features of this synthesis include a β-selective noviosylation, a β-selective …
Non-antibiotic therapy for Clostridioides difficile infection: a review
J Yang, H Yang - Critical reviews in clinical laboratory sciences, 2019 - Taylor & Francis
Clostridioides difficile infection (CDI) is a common infectious disease that is mainly caused
by antibiotics. Antibiotic therapy is still the dominant treatment for CDI, although it is …
by antibiotics. Antibiotic therapy is still the dominant treatment for CDI, although it is …
Fidaxomicin monotherapy versus standard therapy combined with bezlotoxumab for treating patients with Clostridioides difficile infection at high risk of recurrence: a …
R Escudero-Sanchez, A Muriel García… - Journal of …, 2022 - academic.oup.com
Background Both fidaxomicin and bezlotoxumab (used in combination with an antibiotic
against Clostridioides difficile) achieve reductions in recurrence rates of C. difficile infection …
against Clostridioides difficile) achieve reductions in recurrence rates of C. difficile infection …
Mortality, healthcare resource utilization, and cost among Medicare beneficiaries with Clostridioides difficile infection with and without sepsis
A Amin, WW Nelson, J Dreyfus… - Therapeutic …, 2022 - journals.sagepub.com
Objective: To describe mortality, healthcare resource utilization (HRU), and costs among
Medicare beneficiaries with primary Clostridioides difficile infection (pCDI) or recurrent CDI …
Medicare beneficiaries with primary Clostridioides difficile infection (pCDI) or recurrent CDI …
Hypoalbuminemia as predictor of recurrence of Clostridium difficile infection
Summary Background Novel drugs for Clostridium difficile (C. difficile) infections have been
proven to reduce recurrent infections. Because of their high financial costs, identification of …
proven to reduce recurrent infections. Because of their high financial costs, identification of …
Hospital readmission with Clostridium difficile infection as a secondary diagnosis is associated with worsened outcomes and greater revenue loss relative to principal …
MD Zilberberg, BH Nathanson, S Marcella… - Medicine, 2018 - journals.lww.com
Hospital readmission with Clostridium difficile infection as... : Medicine Hospital readmission
with Clostridium difficile infection as a secondary diagnosis is associated with worsened …
with Clostridium difficile infection as a secondary diagnosis is associated with worsened …