Mesenchymal stem cells for the treatment of neurodegenerative disease

N Joyce, G Annett, L Wirthlin, S Olson… - Regenerative …, 2010 - Taylor & Francis
Mesenchymal stem cells/marrow stromal cells (MSCs) present a promising tool for cell
therapy, and are currently being tested in US FDA-approved clinical trials for myocardial …

[HTML][HTML] Galectin 3 as a guardian of the tumor microenvironment

PP Ruvolo - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2016 - Elsevier
Galectin 3 is a member of a family of β-galactoside binding proteins and has emerged as an
important regulator of diverse functions critical in cancer biology including apoptosis …

[HTML][HTML] Cancer associated fibroblasts: the dark side of the coin

P Cirri, P Chiarugi - American journal of cancer research, 2011 - ncbi.nlm.nih.gov
Valid experimental evidence has recently shown that progression of malignant tumors does
not depend exclusively on cell-autonomous properties of the cancer cells, but is also deeply …

Direct evidence of mesenchymal stem cell tropism for tumor and wounding microenvironments using in vivo bioluminescent imaging

S Kidd, E Spaeth, JL Dembinski, M Dietrich… - Stem …, 2009 - academic.oup.com
Multipotent mesenchymal stromal/stem cells (MSC) have shown potential clinical utility.
However, previous assessments of MSC behavior in recipients have relied on visual …

[HTML][HTML] Extracellular vesicle-mediated delivery of miR-101 inhibits lung metastasis in osteosarcoma

K Zhang, C Dong, M Chen, T Yang, X Wang, Y Gao… - Theranostics, 2020 - ncbi.nlm.nih.gov
Abstract Rationale: Extracellular vesicles (EVs) have emerged as novel mediators of cell-to-
cell communication that are capable of the stable transfer of therapeutic microRNAs …

[HTML][HTML] Repair of tissues by adult stem/progenitor cells (MSCs): controversies, myths, and changing paradigms

DJ Prockop - Molecular Therapy, 2009 - cell.com
Research on stem cells has progressed at a rapid pace and, as might be anticipated, the
results have generated several controversies, a few myths and a change in a major …

Bone marrow-derived mesenchymal stem cells and the tumor microenvironment

SA Bergfeld, YA DeClerck - Cancer and Metastasis Reviews, 2010 - Springer
Over the last decade, there has been a growing interest in the role of mesenchymal stem
cells (MSC) in cancer progression. These cells have the potential to give rise to a variety of …

Non-genetic engineering of cells for drug delivery and cell-based therapy

Q Wang, H Cheng, H Peng, H Zhou, PY Li… - Advanced drug delivery …, 2015 - Elsevier
Cell-based therapy is a promising modality to address many unmet medical needs. In
addition to genetic engineering, material-based, biochemical, and physical science-based …

The design and use of animal models for translational research in bone tissue engineering and regenerative medicine

GF Muschler, VP Raut, TE Patterson… - … Engineering Part B …, 2010 - liebertpub.com
This review provides an overview of animal models for the evaluation, comparison, and
systematic optimization of tissue engineering and regenerative medicine strategies related …

Evolving paradigms for repair of tissues by adult stem/progenitor cells (MSCs)

DJ Prockop, DJ Kota, N Bazhanov… - Journal of cellular and …, 2010 - Wiley Online Library
Paradigm I: the haematopoietic niche• Paradigm II: engraftment/differentiation‐Early
observations on engraftment and differentiation‐Technical challenges in testing paradigm II …