Cell collectives must dynamically adapt to different biological contexts. For instance, in
homeostatic conditions, epithelia must establish a barrier between body compartments and …

Among the defining features of the animal kingdom is the ability of cells to change shape
and move. This underlies embryonic and postembryonic development, tissue homeostasis …

The inner layer of blood vessels consists of endothelial cells, which form the physical barrier
between blood and tissue. This vascular barrier is tightly regulated and is defined by cell-cell …

In addition to biochemical and electrochemical signaling, cells also rely extensively on
mechanical signaling to regulate their behavior. While a number of tools have been adapted …

Rapid epithelial tissue flows are essential to building and shaping developing embryos.
However, the mechanical properties of embryonic epithelial tissues and the factors that …

Modern biology and biomedicine are undergoing a big data explosion, needing advanced
computational algorithms to extract mechanistic insights on the physiological state of living …

Neural tube closure (NTC) is a fundamental process during vertebrate development and is
indispensable for the formation of the central nervous system. Here, using Xenopus laevis …

Cells communicate with each other to jointly regulate cellular processes during cellular
differentiation and tissue morphogenesis. This multiscale coordination arises through the …

The initiation of apical-basal (AB) polarity and the process of mitotic cell division are both
characterised by the generation of specialised plasma membrane and cortical domains …

During early development, myosin II mechanically reshapes and folds embryo tissue. A
muchstudied example is ventral furrow formation in Drosophila, marking the onset of …