Defining and combating antibiotic resistance from One Health and Global Health perspectives

S Hernando-Amado, TM Coque, F Baquero… - Nature …, 2019 - nature.com
Several interconnected human, animal and environmental habitats can contribute to the
emergence, evolution and spread of antibiotic resistance, and the health of these contiguous …

Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria

RV Sionov, D Steinberg - Microorganisms, 2022 - mdpi.com
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

A broad-spectrum antibiotic adjuvant reverses multidrug-resistant Gram-negative pathogens

M Song, Y Liu, X Huang, S Ding, Y Wang, J Shen… - Nature …, 2020 - nature.com
The rapid emergence and dissemination of multidrug-resistant (MDR) bacterial pathogens
pose a serious threat to global healthcare. One particular concern is the carbapenem …

A 0D-2D heterojunction bismuth molybdate-anchored multifunctional hydrogel for highly efficient eradication of drug-resistant bacteria

X Wang, Q Li, Y Miao, X Chen, X Zhang, J Shi, F Liu… - ACS …, 2023 - ACS Publications
Due to the increasing antibiotic resistance and the lack of broad-spectrum antibiotics, there
is an urgent requirement to develop fresh strategies to combat multidrug-resistant …

Exploring the Role of Staphylococcus aureus in Inflammatory Diseases

H Chen, J Zhang, Y He, Z Lv, Z Liang, J Chen, P Li… - Toxins, 2022 - mdpi.com
Staphylococcus aureus is a very common Gram-positive bacterium, and S. aureus infections
play an extremely important role in a variety of diseases. This paper describes the types of …

Recent advances in anti-virulence therapeutic strategies with a focus on dismantling bacterial membrane microdomains, toxin neutralization, quorum-sensing …

O Fleitas Martínez, MH Cardoso, SM Ribeiro… - Frontiers in cellular …, 2019 - frontiersin.org
Antimicrobial resistance constitutes one of the major challenges facing humanity in the
Twenty-First century. The spread of resistant pathogens has been such that the possibility of …

[HTML][HTML] Drug repurposing for next-generation combination therapies against multidrug-resistant bacteria

Y Liu, Z Tong, J Shi, R Li, M Upton, Z Wang - Theranostics, 2021 - ncbi.nlm.nih.gov
Antimicrobial resistance has been a global health challenge that threatens our ability to
control and treat life-threatening bacterial infections. Despite ongoing efforts to identify new …

Staphylococcal biofilms: Challenges and novel therapeutic perspectives

C Kranjec, D Morales Angeles, M Torrissen Mårli… - Antibiotics, 2021 - mdpi.com
Staphylococci, like Staphylococcus aureus and S. epidermidis, are common colonizers of
the human microbiota. While being harmless in many cases, many virulence factors result in …

Evolutionary mechanisms shaping the maintenance of antibiotic resistance

P Durão, R Balbontín, I Gordo - Trends in microbiology, 2018 - cell.com
Antibiotics target essential cellular functions but bacteria can become resistant by acquiring
either exogenous resistance genes or chromosomal mutations. Resistance mutations …

Antibiotic resistance: moving from individual health norms to social norms in one health and global health

S Hernando-Amado, TM Coque, F Baquero… - Frontiers in …, 2020 - frontiersin.org
Antibiotic resistance is a problem for human health, and consequently, its study had been
traditionally focused toward its impact for the success of treating human infections in …