Oxidative stress and mitochondrial dysfunction in chronic kidney disease

HJ Ho, H Shirakawa - Cells, 2022 - mdpi.com
The kidney contains many mitochondria that generate ATP to provide energy for cellular
processes. Oxidative stress injury can be caused by impaired mitochondria with excessive …

Environmental pollutants induce NLRP3 inflammasome activation and pyroptosis: roles and mechanisms in various diseases

Y Mou, W Liao, Y Liang, Y Li, M Zhao, Y Guo… - Science of The Total …, 2023 - Elsevier
Environmental pollution is changing with economic development. Most environmental
pollutants are characterized by stable chemical properties, strong migration, potential …

Endoplasmic reticulum stress-mediated autophagy activation is involved in cadmium-induced ferroptosis of renal tubular epithelial cells

C Zhao, D Yu, Z He, L Bao, L Feng, L Chen… - Free Radical Biology …, 2021 - Elsevier
Acute cadmium (Cd) exposure is a significant risk factor for renal injury and lacks effective
treatment strategies. Ferroptosis is a recently identified iron-dependent form of nonapoptotic …

[HTML][HTML] Pig lung fibrosis is active in the subacute CdCl2 exposure model and exerts cumulative toxicity through the M1/M2 imbalance

S Xu, L Xiaojing, S Xinyue, C Wei, L Honggui… - Ecotoxicology and …, 2021 - Elsevier
Environmental pollutant cadmium (Cd) can cause macrophage dysfunction, and the
imbalance of M1/M2 is involved in the process of tissue fibrosis. In order to explore the effect …

[HTML][HTML] Combined cytotoxicity of polystyrene nanoplastics and phthalate esters on human lung epithelial A549 cells and its mechanism

Q Shi, J Tang, L Wang, R Liu, JP Giesy - Ecotoxicology and environmental …, 2021 - Elsevier
Awareness of risks posed by widespread presence of nanoplastics (NPs) and bioavailability
and potential to interact with organic pollutants has been increasing. Inhalation is one of the …

Chlorpyrifos induces the apoptosis and necroptosis of L8824 cells through the ROS/PTEN/PI3K/AKT axis

L Wang, L Wang, X Shi, S Xu - Journal of hazardous materials, 2020 - Elsevier
Excessive chlorpyrifos (CPF) in the environment causes toxicity to nontarget organisms by
triggering oxidative stress. Phosphatase and tensin homolog deleted on chromosome ten …

[HTML][HTML] Bisphenol A (BPA), BPS and BPB-induced oxidative stress and apoptosis mediated by mitochondria in human neuroblastoma cell lines

C Wang, J He, T Xu, H Han, Z Zhu, L Meng… - Ecotoxicology and …, 2021 - Elsevier
The analogues of biphenol A (BPA), including bisphenol S (BPS) and bisphenol B (BPB),
are commonly used to replace the application of BPA in containers and wrappers of daily …

Role of molybdenum in material immunomodulation and periodontal wound healing: Targeting immunometabolism and mitochondrial function for macrophage …

XT He, X Li, M Zhang, BM Tian, LJ Sun, CS Bi… - Biomaterials, 2022 - Elsevier
Recently, strategies that can target the underlying mechanisms of phenotype change to
modulate the macrophage immune response from the standpoint of biological science have …

Cadmium induces renal inflammation by activating the NLRP3 inflammasome through ROS/MAPK/NF-κB pathway in vitro and in vivo

Z Li, H Chi, W Zhu, G Yang, J Song, L Mo, Y Zhang… - Archives of …, 2021 - Springer
Cadmium (Cd) has been reported to induce kidney damage by triggering oxidative stress
and inflammation. The NLR family Pyrin Domain Containing 3 (NLRP3) inflammasome has …

Cadmium exposure induces pyroptosis in testicular tissue by increasing oxidative stress and activating the AIM2 inflammasome pathway

J Zhou, L Zeng, Y Zhang, M Wang, Y Li, Y Jia… - Science of The Total …, 2022 - Elsevier
High doses of cadmium (Cd) cause irreversible injury to the reproductive system, especially
testicular tissue. Studies have shown that pyroptosis is involved in Cd-induced tissue …