Teeth play essential roles in life. Their development relies on reciprocal interactions
between the ectoderm-derived dental epithelium and the underlying neural crest-originated …

The human body is covered with several million sweat glands. These tiny coiled tubular skin
appendages produce the sweat that is our primary source of cooling and hydration of the …

Tissue stem cells are generated from a population of embryonic progenitors through organ-
specific morphogenetic events,. Although tissue stem cells are central to organ homeostasis …

De novo organ regeneration has been observed in several lower organisms, as well as
rodents; however, demonstrating these regenerative properties in human cells and tissues …

We report a genome-wide association scan in over 6,000 Latin Americans for features of
scalp hair (shape, colour, greying, balding) and facial hair (beard thickness, monobrow …

The embryonic surface ectoderm gives rise to the epidermis and ectodermal appendages
including hair follicles, teeth, scales, feathers, and mammary, sweat, and salivary glands …

In hair follicle development, a placode-derived signal is believed to induce formation of the
dermal condensation, an essential component of ectodermal organs. However, the identity …

How dermal papilla (DP) niche cells regulate hair follicle progenitors to control hair growth
remains unclear. Using Tbx18 Cre to target embryonic DP precursors, we ablate the …

Embryonic mammary gland development involves the formation of mammary placodes,
invagination of flask-shaped mammary buds and development of miniature bi-layered ductal …

Organ size and numbers are vital issues in bioengineering for hair follicle (HF) regeneration.
Murine HF dermal papilla (DP) cells are able to induce HF neogenesis when transplanted …