Diabetes mellitus and the associated complications are metabolic diseases with high
morbidity that result in poor quality of health and life. The lack of diagnostic methods for early …

Hepatitis viruses are chief pathogens of hepatitis and end-stage liver diseases. Their
replication and related pathogenic process highly rely on the host micro-environment and …

In December 2019, an outbreak of atypical pneumonia (Coronavirus disease 2019-COVID-
19) associated with a novel coronavirus (SARS-CoV-2) was reported in Wuhan city, Hubei …

Arthropod-borne viruses pose a major threat to global public health. Thus, innovative
strategies for their control and prevention are urgently needed. Here, we exploit the natural …

In diverse viral infections, the production of excess viral particles containing only viral
glycoproteins (subviral particles or SVP) is commonly observed and is a commonly evolved …

The hepatitis C virus (HCV) causes severe liver diseases, including hepatitis, liver cirrhosis,
and hepatocellular carcinoma, which have high morbidity and mortality. Antibody targeting …

Background It is estimated that up to 80% of infections caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) are asymptomatic and asymptomatic patients can …

Early innate viral recognition by the host is critical for the rapid response and subsequent
clearance of an infection. Innate immune cells patrol sites of infection to detect and respond …

RNA genetic elements include many important animal and plant pathogens. They share
high mutability, a trait that has multiple implications for the interactions with their host …

Two recent studies documented the genome of a novel, extremely large (35.9 kb), nidovirus
in RNA sequence databases from the marine neural model Aplysia californica. The goal of …