The impact of maternal folates on brain development and function after birth

S Virdi, NM Jadavji - Metabolites, 2022 - mdpi.com
Folate is vital for biological processes within the body, including DNA synthesis, DNA repair,
and methylation reactions that metabolize homocysteine. The role of folate is particularly …

Folate administration ameliorates neurobehavioral effects of prenatal ethanol exposure

L Marengo, MC Fabio, IS Bernal… - The American journal …, 2023 - Taylor & Francis
Background: Prenatal ethanol exposure (PEE) induces heightened ethanol intake at
adolescence in preclinical studies. Ethanol intake alters the absorption of folate, a methyl …

[HTML][HTML] Prenatal LPS exposure increases hippocampus IL-10 and prevents short-term memory loss in the male adolescent offspring of high-fat diet fed dams

A Rocha-Gomes, AE Teixeira, CMO Santiago… - Physiology & …, 2022 - Elsevier
Lipopolysaccharide (LPS) tolerance can reduce the neuroinflammation caused by high fat
maternal diets; however, there are no reports that have evaluated the effects of prenatal LPS …

Folic acid deficiency exacerbates the inflammatory response of astrocytes after ischemia‐reperfusion by enhancing the interaction between IL‐6 and JAK‐1/pSTAT3

M Cheng, X Liang, L Shi, Q Zhang… - CNS Neuroscience …, 2023 - Wiley Online Library
Aim To demonstrate the role of IL‐6 and pSTAT3 in the inflammatory response to cerebral
ischemia/reperfusion following folic acid deficiency (FD). Methods The middle cerebral …

Neurobehavioral alterations induced by third‐trimester gestation‐equivalent ethanol exposure are inhibited by folate administration

L Marengo, A Barey, A Salguero… - Developmental …, 2023 - Wiley Online Library
Prenatal ethanol exposure (PEE) causes several neurobehavioral impairments in the fetus.
Postnatal days (PDs) 4–9 in rodents are considered equivalent to the third trimester of …

Molecular mechanisms of cognitive impairment in a maternal immune activation model for schizophrenia in the rat

RM Woods - 2023 - search.proquest.com
Schizophrenia is a debilitating neuropsychiatric disorder with heterogenous symptoms
across three key domains: positive, negative and cognitive symptoms. Current therapeutic …