The early diagnosis of systemic sclerosis (SSc) can be very difficult, when most of the typical
signs and symptoms are absent. For this reason, the approach to SSc has changed during …

Background Systemic sclerosis-associated interstitial lung disease (ILD) carries a high
mortality risk; expert guidance is required to aid early recognition and treatment. We aimed …

The diagnostic assessment of patients with Interstitial Lung Disease (ILD) can be
challenging due to the large number of possible causes. Moreover, the diagnostic approach …

Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by dysregulation of
the immune system, vascular damage, and fibrosis of the skin and internal organs. Patients …

Aim Patients with systemic sclerosis (SSc) are at increased risk of cancer, a growing cause
of non–SSc-related death among these patients. We analyzed the increased cancer risk …

This systematic review summarises current evidence to help guide treatment decisions for
patients with systemic sclerosis (SSc)-associated interstitial lung disease (ILD). A systematic …

Objective: to describe the prevalences, characteristics, and survivals of patients with anti-
topoisomerase 1 antibodies (ATA) and limited cutaneous systemic sclerosis (lSSc) and anti …

Introduction Systemic sclerosis is a chronic and progressive connective tissue disease with
various manifestation. Inflammatory status is developed in early stages and is followed by …

Objective. Scleroderma renal crisis (SRC) is a severe life-threatening manifestation in
patients with systemic sclerosis (SSc). However, the knowledge about risk factors for SRC is …

Scleroderma renal crisis (SRC) is an acute life-threatening manifestation of systemic
sclerosis (SSc) caused by obliterative vasculopathy and thrombotic microangiopathy …