The intestine harbours a complex array of microorganisms collectively known as the gut
microbiota. The past two decades have witnessed increasing interest in studying the gut …

This new diagnostic consensus guideline is a joint project of the European Crohn's and
Colitis Organisation [ECCO] and the European Society of Gastrointestinal and Abdominal …

Crohn's disease is an idiopathic inflammatory disorder of unknown etiology with genetic,
immunologic, and environmental influences. The incidence of Crohn's disease has steadily …

Inflammatory bowel diseases (IBDs), including Crohn's disease and ulcerative colitis, are
chronic, progressive, immune-mediated diseases of adults and children that have no cure …

This paper is the second in a series of two publications relating to the European Crohn's and
Colitis Organisation [ECCO] evidence-based consensus on the diagnosis and management …

Objectives: Persistent disease activity is associated with a poor prognosis in inflammatory
bowel disease (IBD). Therefore, monitoring of patients with intent to suppress subclinical …

Summary Background Conventional management of Crohn's disease features incremental
use of therapies. However, early combined immunosuppression (ECI), with a TNF …

Background Mucosal healing is an important therapeutic endpoint in the management of
Crohn's disease (CD) and ulcerative colitis (UC). Limited data exist regarding the …

Although most treatment algorithms in inflammatory bowel disease (IBD) begin with
classifying patients according to disease severity, no formal validated or consensus …

Recent observations suggest that subjective measures of disease activity in inflammatory
bowel disease (IBD) are often misleading. Objective measures of inflammation are more …