Malaria is a life threatening disease caused by microscopic parasites called Plasmodium
that are transmitted to human beings by mosquitoes. Single celled Eukaryotic plasmodium …

This review is intended to highlight the most useful approaches for the synthesis of indole
derivatives (azaindoles, carbazoles, carbolines, indazoles, 3H‐indoles, indolines …

The binding affinity of human serum albumin (HSA) to three antimalarial indolone-N-oxide
derivatives, INODs, was investigated under simulated physiological conditions using …

An oxidative dearomatization chemistry of 2-arylindole via a unique pathway involving Pd-
catalyzed C–H peroxygenation is documented. Coupled with cascade transformation, it …

The homodimeric flavoenzyme glutathione reductase catalyzes NADPH-dependent
glutathione disulfide reduction. This reaction is important for keeping the redox homeostasis …

The chiral amide–guanidine-catalyzed asymmetric formal [3+ 2] cycloaddition of isatogens
with azlactones is presented. This strategy provided a facile and feasible route to chiral …

An efficient and practical method for the synthesis of 2-indolyl indolone N-oxides via gold (I)-
catalyzed cascade reaction of o-nitroalkynes with indoles has been reported. The generated …

Binding of drugs to plasma proteins, such as albumin, is a major factor which determines
their pharmacokinetics and pharmacological effects. Therefore, the interactions between …

More than 40 years after its discovery, artemisinin has become the most promising
antimalarial agent. However, no intravenous formulation is available due to its poor aqueous …

A novel method for the synthesis of C2‐quaternary indole‐3‐ones via palladium‐catalyzed
one‐pot transformation of 2‐alkynyl arylazides is described. The reaction produced in …