The gastrointestinal tract contains its own set of intrinsic neuroglial circuits—the enteric
nervous system (ENS)—which detects and responds to diverse signals from the …

Emerging evidence suggests that alterations in the development of the gastrointestinal (GI)
tract during the early postnatal period can influence brain development and vice-versa. It is …

The enteric nervous system (ENS) forms a versatile sensory system along the
gastrointestinal tract that interacts with most cell types in the bowel. Herein, we portray host …

Infants and young children receive the highest exposures to antibiotics globally. Although
there is building evidence that early life exposure to antibiotics increases susceptibility to …

Interactions between the enteric nervous system (ENS), immune system, and gut microbiota
regulate intestinal homeostasis in adults, but their development and role (s) in early life are …

During embryonic development, the gut is innervated by intrinsic (enteric) and extrinsic
nerves. Focusing on mammalian ENS development, in this Review we highlight how …

Adolescence is a critical period of development. It is very likely that there is significant
maturation of the enteric nervous system (ENS) of the gut during this stage of life, especially …

Recent studies on humans and their key experimental model, the mouse, have begun to
uncover the importance of gastrointestinal (GI) microbiota and enteric nervous system (ENS) …

Of all the organ systems in the body, the gastrointestinal tract is the most complicated in
terms of the numbers of structures involved, each with different functions, and the numbers …

The gastrointestinal tract harbors an intrinsic neuronal network, the enteric nervous system
(ENS). The ENS controls motility, fluid homeostasis, and blood flow, but also interacts with …