Progress in the mechanism and targeted drug therapy for COPD
C Wang, J Zhou, J Wang, S Li, A Fukunaga… - … and Targeted Therapy, 2020 - nature.com
Chronic obstructive pulmonary disease (COPD) is emphysema and/or chronic bronchitis
characterised by long-term breathing problems and poor airflow. The prevalence of COPD …
characterised by long-term breathing problems and poor airflow. The prevalence of COPD …
Shedding a new light on skin aging, iron-and redox-homeostasis and emerging natural antioxidants
C Pourzand, A Albieri-Borges, NN Raczek - Antioxidants, 2022 - mdpi.com
Reactive oxygen species (ROS) are necessary for normal cell signaling and the
antimicrobial defense of the skin. However excess production of ROS can disrupt the cellular …
antimicrobial defense of the skin. However excess production of ROS can disrupt the cellular …
Group A Streptococcus induces CD1a-autoreactive T cells and promotes psoriatic inflammation
YL Chen, JSW Ng, R Ottakandathil Babu, J Woo… - Science …, 2023 - science.org
Group A Streptococcus (GAS) infection is associated with multiple clinical sequelae,
including different subtypes of psoriasis. Such post-streptococcal disorders have been long …
including different subtypes of psoriasis. Such post-streptococcal disorders have been long …
Thioredoxin-1: A promising target for the treatment of allergic diseases
J Wang, J Zhou, C Wang, A Fukunaga, S Li… - Frontiers in …, 2022 - frontiersin.org
Thioredoxin-1 (Trx1) is an important regulator of cellular redox homeostasis that comprises a
redox-active dithiol. Trx1 is induced in response to various stress conditions, such as …
redox-active dithiol. Trx1 is induced in response to various stress conditions, such as …
Peptide-Protected Gold Nanoclusters Efficiently Ameliorate Acute Contact Dermatitis and Psoriasis via Repressing the TNF-α/NF-κB/IL-17A Axis in Keratinocytes
Immune-mediated skin diseases have a high prevalence and seriously affect patients'
quality of life. Gold compounds have been considered promising therapeutic agents in …
quality of life. Gold compounds have been considered promising therapeutic agents in …
Geranylgeranylacetone ameliorates skin inflammation by regulating and inducing thioredoxin via the thioredoxin redox system
T Jin, Y You, W Fan, J Wang, Y Chen, S Li, S Hong… - Antioxidants, 2023 - mdpi.com
Geranylgeranylacetone (GGA) exerts cytoprotective activity against various toxic stressors
via the thioredoxin (TRX) redox system; however, its effect on skin inflammation and …
via the thioredoxin (TRX) redox system; however, its effect on skin inflammation and …
[HTML][HTML] Nasturtium officinale R. Br. effectively reduces the skin inflammation induced by croton oil via glucocorticoid receptor-dependent and NF-κB pathways without …
C Camponogara, CR Silva, I Brusco, M Piana… - Journal of …, 2019 - Elsevier
Ethnopharmacological relevance Inflammatory skin diseases treatments currently used
cause adverse effects. Nasturtium officinale (watercress) is used popularly as an anti …
cause adverse effects. Nasturtium officinale (watercress) is used popularly as an anti …
Anti-allergic and anti-inflammatory effects and molecular mechanisms of thioredoxin on respiratory system diseases
JD Zhou, CX Wang, JL Wu, A Fukunaga… - Antioxidants & Redox …, 2020 - liebertpub.com
Significance: The pathogenesis and progression of allergic inflammation in the respiratory
system are closely linked to oxidative stress. Thioredoxin (TRX) is an essential redox …
system are closely linked to oxidative stress. Thioredoxin (TRX) is an essential redox …
Anti-inflammatory thioredoxin family proteins for medicare, healthcare and aging care
J Yodoi, Y Matsuo, H Tian, H Masutani, T Inamoto - Nutrients, 2017 - mdpi.com
Human thioredoxin (TRX) is a 12-kDa protein with redox-active dithiol in the active site-Cys-
Gly-Pro-Cys-, which is induced by biological stress due to oxidative damage, metabolic …
Gly-Pro-Cys-, which is induced by biological stress due to oxidative damage, metabolic …
Thioredoxin‐1 and its mimetic peptide improve systolic cardiac function and remodeling after myocardial infarction
T Medali, D Couchie, N Mougenot, M Mihoc… - The FASEB …, 2024 - Wiley Online Library
Myocardial infarction (MI) is characterized by a significant loss of cardiomyocytes (CMs), and
it is suggested that reactive oxygen species (ROS) are involved in cell cycle arrest, leading …
it is suggested that reactive oxygen species (ROS) are involved in cell cycle arrest, leading …