Cu (I)-catalyzed click chemistry in glycoscience and their diverse applications
Copper (I)-catalyzed 1, 3-dipolar cycloaddition between organic azides and terminal
alkynes, commonly known as CuAAC or click chemistry, has been identified as one of the …
alkynes, commonly known as CuAAC or click chemistry, has been identified as one of the …
Cu-catalyzed click reaction in carbohydrate chemistry
Cu (I)-catalyzed azide–alkyne 1, 3-dipolar cycloaddition (CuAAC), popularly known as the
“click reaction”, serves as the most potent and highly dependable tool for facile construction …
“click reaction”, serves as the most potent and highly dependable tool for facile construction …
Thermostability, tunability, and tenacity of RNA as rubbery anionic polymeric materials in nanotechnology and nanomedicine—specific cancer targeting with …
RNA nanotechnology is the bottom-up self-assembly of nanometer-scale architectures,
resembling LEGOs, composed mainly of RNA. The ideal building material should be (1) …
resembling LEGOs, composed mainly of RNA. The ideal building material should be (1) …
Selective inhibition of ADAR1 using 8-azanebularine-modified RNA duplexes
HG Mendoza, VJ Matos, SH Park, KM Pham… - Biochemistry, 2023 - ACS Publications
Adenosine deaminases acting on RNA (ADARs) are RNA editing enzymes that catalyze the
hydrolytic deamination of adenosine (A) to inosine (I) in dsRNA. In humans, two catalytically …
hydrolytic deamination of adenosine (A) to inosine (I) in dsRNA. In humans, two catalytically …
Synthesis and cellular activity of stereochemically-pure 2′-O-(2-methoxyethyl)-phosphorothioate oligonucleotides
M Li, HL Lightfoot, F Halloy, AL Malinowska… - Chemical …, 2017 - pubs.rsc.org
Stereochemically-pure 2′-O-(2-methoxyethyl)-phosphorothioate (PS-MOE)
oligonucleotides were synthesized from new chiral oxazaphospholidine-containing …
oligonucleotides were synthesized from new chiral oxazaphospholidine-containing …
Watson–Crick Base Pairs with Protecting Groups: The 2-Amino Groups of Purine-and 7-Deazapurine-2, 6-Diamine as Target Sites for DNA Functionalization by …
D Kondhare, X Heddinga, P Leonard… - Bioconjugate …, 2023 - ACS Publications
The recognition of Watson–Crick base pairs carrying nucleobase protecting groups is
reported as a new approach for DNA functionalization. The 2-amino groups of purine-and 7 …
reported as a new approach for DNA functionalization. The 2-amino groups of purine-and 7 …
Pyrrolo‐dC Metal‐Mediated Base Pairs in the Reverse Watson–Crick Double Helix: Enhanced Stability of Parallel DNA and Impact of 6‐Pyridinyl Residues on …
Abstract Reverse Watson–Crick DNA with parallel‐strand orientation (ps DNA) has been
constructed. Pyrrolo‐dC (PyrdC) nucleosides with phenyl and pyridinyl residues linked to …
constructed. Pyrrolo‐dC (PyrdC) nucleosides with phenyl and pyridinyl residues linked to …
Imidazolo‐dC Metal‐Mediated Base Pairs: Purine Nucleosides Capture Two Ag+ Ions and Form a Duplex with the Stability of a Covalent DNA Cross‐Link
H Mei, SA Ingale, F Seela - Chemistry–A European Journal, 2014 - Wiley Online Library
Phenylimidazolo‐dC (phImidC, 2) forms metal‐mediated DNA base pairs by entrapping two
silver ions. To this end, the fluorescent “purine” 2′‐deoxyribonucleoside 2 has been …
silver ions. To this end, the fluorescent “purine” 2′‐deoxyribonucleoside 2 has been …
A chemical approach to introduce 2, 6-diaminopurine and 2-aminoadenine conjugates into oligonucleotides without need for protecting groups
We report a simple, postsynthetic strategy for synthesis of oligonucleotides containing 2, 6-
diaminopurine nucleotides and 2-aminoadenine conjugates using 2-fluoro-6-amino …
diaminopurine nucleotides and 2-aminoadenine conjugates using 2-fluoro-6-amino …
Gold-like thiolate-protected ultrasmall cubic copper nanocluster-based metal–organic framework as a selective catalyst for stepwise synthesis of unsymmetric …
R Murugan, M Bhargava Reddy… - … Applied Materials & …, 2020 - ACS Publications
We report a facile synthesis of a thiolate-protected water-soluble ultrasmall cubic copper
nanocluster-based metal–organic framework (CuMOF) as an efficient and chemoselective …
nanocluster-based metal–organic framework (CuMOF) as an efficient and chemoselective …