Researchers worldwide are repeatedly warning us against future zoonotic diseases
resulting from humankind's insurgence into natural ecosystems. The same zoonotic …

From flies to humans, many components of the innate immune system have been conserved
during metazoan evolution. This foundational observation has allowed us to develop …

Infectious diseases are mostly explored using reductionist approaches despite repeated
evidence showing them to be strongly influenced by numerous interacting host and …

Antimicrobial peptides (AMPs) are host-encoded antibiotics that combat invading
microorganisms. These short, cationic peptides have been implicated in many biological …

The gut microbiota affects the physiology and metabolism of animals and its alteration can
lead to diseases such as gut dysplasia or metabolic disorders. Several reports have shown …

Retrotransposons are one type of mobile genetic element that abundantly reside in the
genomes of nearly all animals. Their uncontrolled activation is linked to sterility, cancer and …

Host responses to infection encompass many processes in addition to activation of the
immune system, including metabolic adaptations, stress responses, tissue repair, and other …

Over the last decade, innate immune priming has been evidenced in many invertebrate
phyla. If mechanistic models have been proposed, molecular studies aiming to substantiate …

Effective antibiotic use that minimizes treatment failures remains a challenge. A better
understanding of how bacterial populations respond to antibiotics is necessary. Previous …

Host defense against infections encompasses both resistance, which targets
microorganisms for neutralization or elimination, and resilience/disease tolerance, which …