Central nervous system demyelinating diseases: glial cells at the hub of pathology
VG Coutinho Costa, SES Araújo… - Frontiers in …, 2023 - frontiersin.org
Inflammatory demyelinating diseases (IDDs) are among the main causes of inflammatory
and neurodegenerative injury of the central nervous system (CNS) in young adult patients …
and neurodegenerative injury of the central nervous system (CNS) in young adult patients …
Overview of pro-inflammatory and pro-survival components in neuroinflammatory signalling and neurodegeneration
S Kardam, RK Ambasta, P Kumar - Ageing Research Reviews, 2024 - Elsevier
Neurodegenerative diseases (NDDs) are identified by the progressive deterioration of
neurons and a subsequent decline in cognitive function, creating an enormous burden on …
neurons and a subsequent decline in cognitive function, creating an enormous burden on …
Mechanisms underlying the beneficial effects of physical exercise on multiple sclerosis: focus on immune cells
B Zong, F Yu, X Zhang, W Zhao, S Li, L Li - Frontiers in immunology, 2023 - frontiersin.org
Multiple sclerosis (MS) is a prevalent neuroimmunological illness that leads to neurological
disability in young adults. Although the etiology of MS is heterogeneous, it is well …
disability in young adults. Although the etiology of MS is heterogeneous, it is well …
[HTML][HTML] Sex-dependent factors of alcohol and neuroimmune mechanisms
Excessive alcohol use disrupts neuroimmune signaling across various cell types, including
neurons, microglia, and astrocytes. The present review focuses on recent, albeit limited …
neurons, microglia, and astrocytes. The present review focuses on recent, albeit limited …
Microglial Reactivity Correlates with Presynaptic Loss Independent of β‐Amyloid and Tau
Objective Triggering receptor expressed on myeloid cells‐2 (TREM2) and progranulin
(PGRN) are critical regulators of microglia activation and can be detected in cerebrospinal …
(PGRN) are critical regulators of microglia activation and can be detected in cerebrospinal …
Aphanizomenon flos-aquae (AFA) Extract Prevents Neurodegeneration in the HFD Mouse Model by Modulating Astrocytes and Microglia Activation
Obesity and related metabolic dysfunctions are associated with neurodegenerative
diseases, such as Alzheimer's disease. Aphanizomenon flos-aquae (AFA) is a …
diseases, such as Alzheimer's disease. Aphanizomenon flos-aquae (AFA) is a …
[HTML][HTML] Establishing normal serum values of neurofilament light chains and glial fibrillary acidic protein considering the effects of age and other demographic factors …
A Rodero-Romero, E Monreal, R Sainz-Amo… - International Journal of …, 2024 - mdpi.com
Multiple studies have shown the importance of blood-based biomarkers indicating axonal
damage (serum neurofilament light chains [sNfL]) or astroglia activation (serum glial fibrillary …
damage (serum neurofilament light chains [sNfL]) or astroglia activation (serum glial fibrillary …
Diagnostic utility of cerebrospinal fluid biomarkers in patients with rapidly progressive dementia
LA Kuchenbecker, PW Tipton, Y Martens… - Annals of …, 2024 - Wiley Online Library
Objective This study was undertaken to apply established and emerging cerebrospinal fluid
(CSF) biomarkers to improve diagnostic accuracy in patients with rapidly progressive …
(CSF) biomarkers to improve diagnostic accuracy in patients with rapidly progressive …
Exploring the management approaches of cytokines including viral infection and neuroinflammation for neurological disorders
Considerable evidence supports that cytokines are important mediators of pathophysiologic
processes within the central nervous system (CNS). Numerous studies have documented …
processes within the central nervous system (CNS). Numerous studies have documented …
Soluble TREM2 is a potential biomarker for the severity of primary angiitis of the CNS
T Guo, J Ma, J Sun, W Xu, H Cong, Y Wei… - Frontiers in …, 2022 - frontiersin.org
Background Primary angiitis of the central nervous system (PACNS) is a severe
inflammatory disease, and soluble triggering receptor expressed on myeloid cells 2 …
inflammatory disease, and soluble triggering receptor expressed on myeloid cells 2 …