Structural and functional roles of 2'-O-ribose methylations and their enzymatic machinery across multiple classes of RNAs
S Höfler, T Carlomagno - Current Opinion in Structural Biology, 2020 - Elsevier
Highlights•Differential levels of 2'-O-methylation in rRNA might contribute to ribosome
specialization in different cell types.•rRNA methylation levels are controlled by regRNPs and …
specialization in different cell types.•rRNA methylation levels are controlled by regRNPs and …
Multi-adductomics: Advancing mass spectrometry techniques for comprehensive exposome characterization
Adductomics, an emerging field within the'omics sciences, focuses on the formation and
prevalence of DNA, RNA, and protein adducts induced by endogenous and exogenous …
prevalence of DNA, RNA, and protein adducts induced by endogenous and exogenous …
Exploring Glycosylated Soy Isoflavones Affinities toward G‐tetrads as Studied by Survival Yield Method
O Stężycka, M Frańska… - …, 2023 - Wiley Online Library
Taking soy‐based food supplements for menopausal symptoms by women may reduce the
risk of cancer. Therefore, the interaction between nucleic acids (or their constituents) and …
risk of cancer. Therefore, the interaction between nucleic acids (or their constituents) and …
Structural determination of arginine-linked cisplatin complexes via IRMPD action spectroscopy: arginine binds to platinum via NO− binding mode
Cisplatin,(NH3) 2PtCl2, has been known as a successful metal-based anticancer drug for
more than half a century. Its analogue, Argplatin, arginine-linked cisplatin,(Arg) PtCl2, is …
more than half a century. Its analogue, Argplatin, arginine-linked cisplatin,(Arg) PtCl2, is …
Influence of 5-fluorination on the structure and glycosidic bond stability of the protonated canonical DNA and RNA cytidine nucleosides: Oh, what a difference the 2 …
Fluorinated nucleosides are well-established as anticancer and antiviral medications. As
with many pharmaceuticals, the effects of fluorine modifications are often only partially …
with many pharmaceuticals, the effects of fluorine modifications are often only partially …
Protonation-induced tautomerization lowers the activation barriers for N-glycosidic bond cleavage of thymidine and 5-methyluridine
RR Wu, MT Rodgers - International Journal of Mass Spectrometry, 2025 - Elsevier
Synergistic infrared multiple photon dissociation (IRMPD) action spectroscopy experiments
and electronic structure calculations revealed that both 2, 4-dihydroxy tautomers and O2 …
and electronic structure calculations revealed that both 2, 4-dihydroxy tautomers and O2 …
5-Halogenation of Uridine Suppresses Protonation-Induced Tautomerization and Enhances Glycosidic Bond Stability of Protonated Uridine: Investigations via IRMPD …
Uridine (Urd), a canonical nucleoside of RNA, is the most commonly modified nucleoside
among those that occur naturally. Uridine has also been an important target for the …
among those that occur naturally. Uridine has also been an important target for the …
Influence of 5-Halogenation on the Base-Pairing Energies of Protonated Cytidine Nucleoside Analogue Base Pairs: Implications for the Stabilities of Synthetic i-Motif …
MT Rodgers, YS Seidu, E Israel - … of the American Society for Mass …, 2022 - ACS Publications
DNA nanotechnology has been employed to develop devices based on i-motif structures.
The protonated cytosine-cytosine base pairs that stabilize i-motif conformations are favored …
The protonated cytosine-cytosine base pairs that stabilize i-motif conformations are favored …
Identification of 2'-O-methylation site by investigating multi-feature extracting techniques
QL Huang, L Wang, SG Han… - … Chemistry & High …, 2020 - ingentaconnect.com
Background: RNA methylation is a reversible post-transcriptional modification involving
numerous biological processes. Ribose 2'-O-methylation is part of RNA methylation. It has …
numerous biological processes. Ribose 2'-O-methylation is part of RNA methylation. It has …
Characterization of Protonated Modified Nucleosides and Amino Acid-Linked Cisplatin Analogues Using Tandem Mass Spectrometry Complemented By Theoretical …
C He - 2018 - search.proquest.com
The chemical difference between DNA and RNA nucleosides is their 2'-hydrogen versus 2'-
hydroxyl substituents. The 2'-O-methylation is common among natural posttranscriptional …
hydroxyl substituents. The 2'-O-methylation is common among natural posttranscriptional …