[HTML][HTML] Imaging-assisted anticancer nanotherapy
Cancer nanomedicines are submicrometer-sized formulations designed to improve the
biodistribution of anticancer drugs, resulting in less off-target localization, altered toxicity …
biodistribution of anticancer drugs, resulting in less off-target localization, altered toxicity …
Sonoporation enhances liposome accumulation and penetration in tumors with low EPR
Abstract The Enhanced Permeability and Retention (EPR) effect is a highly variable
phenomenon. To enhance EPR-mediated passive drug targeting to tumors, several different …
phenomenon. To enhance EPR-mediated passive drug targeting to tumors, several different …
Standardization of small animal imaging—current status and future prospects
The benefit of small animal imaging is directly linked to the validity and reliability of the
collected data. If the data (regardless of the modality used) are not reproducible and/or …
collected data. If the data (regardless of the modality used) are not reproducible and/or …
[HTML][HTML] Imalytics preclinical: interactive analysis of biomedical volume data
A software tool is presented for interactive segmentation of volumetric medical data sets. To
allow interactive processing of large data sets, segmentation operations, and rendering are …
allow interactive processing of large data sets, segmentation operations, and rendering are …
Optical imaging of the whole-body to cellular biodistribution of clinical-stage PEG-b-pHPMA-based core-crosslinked polymeric micelles
Core-crosslinked polymeric micelles (CCPM) based on PEG-b-pHPMA-lactate are clinically
evaluated for the treatment of cancer. We macroscopically and microscopically investigated …
evaluated for the treatment of cancer. We macroscopically and microscopically investigated …
[图书][B] Small animal imaging: basics and practical guide
F Kiessling, BJ Pichler - 2010 - books.google.com
Small animal imaging has been recognized as an important tool in preclinical research.
Nevertheless, the results of non-invasive imaging are often disappointing owing to choice of …
Nevertheless, the results of non-invasive imaging are often disappointing owing to choice of …
Balancing passive and active targeting to different tumor compartments using riboflavin-functionalized polymeric nanocarriers
Y Tsvetkova, N Beztsinna, M Baues, D Klein, A Rix… - Nano …, 2017 - ACS Publications
Riboflavin transporters (RFTs) and the riboflavin carrier protein (RCP) are highly
upregulated in many tumor cells, tumor stem cells, and tumor neovasculature, which makes …
upregulated in many tumor cells, tumor stem cells, and tumor neovasculature, which makes …
GPU-accelerated sparse matrix-matrix multiplication by iterative row merging
We present an algorithm for general sparse matrix-matrix multiplication (SpGEMM) on many-
core architectures, such as GPUs. SpGEMM is implemented by iterative row merging, similar …
core architectures, such as GPUs. SpGEMM is implemented by iterative row merging, similar …
CCL2 chemokine inhibition primes the tumor vasculature for improved nanomedicine delivery and efficacy
D Möckel, M Bartneck, P Niemietz, M Wagner… - Journal of Controlled …, 2024 - Elsevier
Blood vessel functionality is crucial for efficient tumor-targeted drug delivery. Heterogeneous
distribution and perfusion of angiogenic blood vessels contribute to suboptimal …
distribution and perfusion of angiogenic blood vessels contribute to suboptimal …
Targeting distinct myeloid cell populations in vivo using polymers, liposomes and microbubbles
Identifying intended or accidental cellular targets for drug delivery systems is highly relevant
for evaluating therapeutic and toxic effects. However, limited knowledge exists on the …
for evaluating therapeutic and toxic effects. However, limited knowledge exists on the …