RNA-dependent DEAD-box ATPases (DDXs) are emerging as major regulators of RNA-
containing membrane-less organelles (MLOs). On the one hand, oligomerizing DDXs can …

Cell cycle is regulated through numerous signaling pathways that determine whether cells
will proliferate, remain quiescent, arrest, or undergo apoptosis. Abnormal cell cycle …

On 15–16 November 2021, the National Institute of Allergy and Infectious Diseases (NIAID),
the National Cancer Institute (NCI) and the National Heart, Lung, and Blood Institute (NHLBI) …

Stress-responsive genes are lowly transcribed under normal conditions and robustly
induced in response to stress. The significant difference between basal and induced …

Rationale: Hepatocellular carcinoma (HCC) is a primary malignancy of the liver that is the
leading cause of cancer-related mortality worldwide. However, genetic alterations and …

Planarians have a remarkable ability to undergo whole-body regeneration. Successful
regeneration outcome is determined by processes like polarity establishment at the wound …

DEAD-box proteins are a large family of RNA helicases that play important roles in almost all
cellular RNA processes in model plants. However, little is known about this family of proteins …

ABSTRACT DEAD-box helicase (DDX) family exerts a critical effect on cancer initiation and
progression through alternative splicing, transcription and ribosome biogenesis. Increasing …

Abstract Background The flatworm planarian, Schmidtea mediterranea, has a large
population of adult stem cells (ASCs) that replace any cell type during tissue turnover or …

The MCF-7R breast cancer cell line, developed by treating the parental MCF-7 cells with
increasing doses of doxorubicin, serves as a model for studying acquired multidrug …