Over the past decade, non-coding RNA-based therapeutics have proven as a great potential
for the development of targeted therapies for cancer and other diseases. The discovery of …

Short interfering RNAs (siRNAs), as small non-coding RNA fragments, are one of the widely
studied RNAi inducers for gene modulations. The reasonably designed siRNA probes …

Traditionally majority of eukaryotic gene expression is influenced by transcriptional and post-
transcriptional events. Alterations in the expression of proteins that act post-transcriptionally …

Ovarian cancer (OC) is considered fifth-deadliest cancer globally responsible for high
mortality in women. As the conventional therapeutic and diagnostic approaches are …

The control of eukaryotic gene expression occurs at multiple levels, from transcription to
messenger RNA processing, transport, localization, turnover, and translation. RNA-binding …

Advancements in the clinical applications of small interfering RNA (siRNA) in cancer therapy
have opened up new possibilities for precision medicine. siRNAs, as powerful genetic tools …

Regulation of cellular oxidative stress plays a critical role in revealing the molecular
mechanisms of cellular activities and thus is a potential strategy for tumor treatment. Optical …

Introduction Among conventional and novel therapeutic approaches, the siRNA strategy
stands out for treating disease by silencing the gene responsible for the corresponding …

Background Cancer development is associated with abnormal, uncontrolled cell growth and
causes significant economic and social burdens to society. The global statistics of different …

RNAi is a remarkable treatment strategy to knock down gene overexpression in a variety of
disorders, including cancers. RNAi processes allow siRNAs to detect and degrade a …