Anti-diabetic actions of glucagon-like peptide-1 on pancreatic beta-cells

YS Lee, HS Jun - Metabolism, 2014 - Elsevier
Abstract Glucagon-like peptide-1 (GLP-1), an incretin hormone, is released from intestinal L-
cells in response to nutrients. GLP-1 lowers blood glucose levels by stimulating insulin …

Stem cell therapy to cure type 1 diabetes: from hype to hope

P Chhabra, KL Brayman - Stem cells translational medicine, 2013 - academic.oup.com
Type 1 diabetes mellitus (T1D) is a chronic, multifactorial autoimmune disease that involves
the progressive destruction of pancreatic β-cells, ultimately resulting in the loss of insulin …

Current status of porcine islet xenotransplantation

TM Coe, JF Markmann, CG Rickert - Current opinion in organ …, 2020 - journals.lww.com
This review will detail the current status of islet xenotransplantation as a potential treatment
for type I diabetes mellitus, focusing on recent advances in porcine xenogeneic islet …

Animal models of diabetes mellitus for islet transplantation

N Sakata, G Yoshimatsu, H Tsuchiya… - Journal of Diabetes …, 2012 - Wiley Online Library
Due to current improvements in techniques for islet isolation and transplantation and
protocols for immunosuppressants, islet transplantation has become an effective treatment …

Transplantation of encapsulated pancreatic islets as a treatment for patients with type 1 diabetes mellitus

M Qi - Advances in medicine, 2014 - Wiley Online Library
Encapsulation of pancreatic islets has been proposed and investigated for over three
decades to improve islet transplantation outcomes and to eliminate the side effects of …

The bioartificial pancreas (BAP): Biological, chemical and engineering challenges

V Iacovacci, L Ricotti, A Menciassi, P Dario - Biochemical pharmacology, 2016 - Elsevier
The bioartificial pancreas (BAP) represents a viable solution for the treatment of type 1
diabetes (T1D). By encapsulating pancreatic cells in a semipermeable membrane to allow …

Beneficial effects of urine-derived stem cells on fibrosis and apoptosis of myocardial, glomerular and bladder cells

X Dong, T Zhang, Q Liu, J Zhu, J Zhao, J Li… - Molecular and cellular …, 2016 - Elsevier
Urine-derived stem cells (USCs) are isolated from voided urine and display high proliferative
activity and multiple differentiation potentials. The applicability of USCs in the treatment of …

Molecular mechanisms of congenital hyperinsulinism

SA Rahman, A Nessa… - Journal of molecular …, 2015 - jme.bioscientifica.com
Diabetes can be managed by careful monitoring of blood glucose and timely delivery of
exogenous insulin. However, even with fastidious compliance, people with diabetes can …

Self-assembled polyelectrolyte complexes of chitosan and fucoidan for sustained growth factor release from PRP enhance proliferation and collagen deposition in …

SS Rao, J Venkatesan, S Yuvarajan… - Drug Delivery and …, 2022 - Springer
Diabetic wound management is a serious health care challenge due to higher rates of
relapse, expensive treatment approaches, and poor healing outcomes. Among cell-based …

Demethylation of induced pluripotent stem cells from type 1 diabetic patients enhances differentiation into functional pancreatic β cells

GS Manzar, EM Kim, N Zavazava - Journal of Biological Chemistry, 2017 - ASBMB
Type 1 diabetes (T1D) can be managed by transplanting either the whole pancreas or
isolated pancreatic islets. However, cadaveric pancreas is scarcely available for clinical use …