Recent advances in the application of ligands in palladium-catalyzed chemoselective coupling reactions at C–Br, C–OTf, and C–Cl sites
This article provides an overview of the development of palladium-catalyzed coupling
reactions and the effects of ligand properties on the chemoselectivity of aryl (pseudo) …
reactions and the effects of ligand properties on the chemoselectivity of aryl (pseudo) …
Recent Advances in Pd‐Catalyzed Suzuki‐Miyaura Cross‐Coupling Reactions with Triflates or Nonaflates
M Degli Innocenti, T Schreiner… - Advanced Synthesis & …, 2023 - Wiley Online Library
Abstract The Pd-catalyzed Suzuki-Miyaura (SM) cross-coupling of organo halides with
organoboron compounds is a widely used tool in organic synthesis for the construction of …
organoboron compounds is a widely used tool in organic synthesis for the construction of …
Organopalladium Catalysis as a Proving Ground for Data-Rich Approaches to Reaction Development and Quantitative Predictions
J Lu, DC Leitch - ACS Catalysis, 2023 - ACS Publications
With the advent of high-throughput methods for both computation and experimentation, data-
rich approaches to discovering and understanding chemical reactions are becoming ever …
rich approaches to discovering and understanding chemical reactions are becoming ever …
Mechanisms and Site Selectivity of (Het) Ar–X Oxidative Addition to Pd (0) Are Controlled by Frontier Molecular Orbital Symmetry
Comparing oxidative addition rates for pairs of 2-chloro-3-EDG-pyridines/2-chloro-5-EDG-
pyridines (EDG= electron-donating group: NH2, OMe, and F) to Pd (PCy3) 2 reveals the 3 …
pyridines (EDG= electron-donating group: NH2, OMe, and F) to Pd (PCy3) 2 reveals the 3 …
Quantitative Reactivity Models for Oxidative Addition to L2Pd(0): Additional Substrate Classes, Solvents, and Mechanistic Insights
J Lu, H Celuszak, I Paci… - Chemistry–A European …, 2024 - Wiley Online Library
Quantitative molecular structure‐reactivity models are useful for generating predictions to
guide synthesis design, and in formulating and testing mechanistic hypotheses. We report …
guide synthesis design, and in formulating and testing mechanistic hypotheses. We report …
Kopplung von Arylchloriden mit Lithium‐Nukleophilen, an molekular definierten Alkynyllithium‐Palladium‐Katalysatoren
JF Goebel, J Stemmer, N Krüger… - Angewandte …, 2024 - Wiley Online Library
Abstract Palladiumkatalysierte Kreuzkupplungen von Arylchloriden erfordern zumeist
sterisch anspruchsvolle, elektronenreiche Liganden wie Phosphine oder heterocyclische …
sterisch anspruchsvolle, elektronenreiche Liganden wie Phosphine oder heterocyclische …
Palladium-Catalyzed Suzuki–Miyaura Reactions with Triazenyl-Tethered Aryl Bromides: Exploiting the Orthogonal Coupling Sites under Different Conditions
Y Li, Z Peng, D Liu, M Pan, Y Shen, H You… - The Journal of …, 2024 - ACS Publications
Transition-metal-catalyzed cross-coupling of arenes bearing two or more potential coupling
sites is often challenging because of the chemoselectivity issue. If orthogonal cross …
sites is often challenging because of the chemoselectivity issue. If orthogonal cross …