Salt sensitivity of blood pressure: a scientific statement from the American Heart Association

F Elijovich, MH Weinberger, CAM Anderson… - …, 2016 - Am Heart Assoc
Hypertension is available at http://hyper. ahajournals. org DOI: 10.1161/HYP.
0000000000000047 e8 Hypertension September 2016 distributed trait. Therefore, defining …

The physiology, signaling, and pharmacology of dopamine receptors

JM Beaulieu, RR Gainetdinov - Pharmacological reviews, 2011 - ASPET
G protein-coupled dopamine receptors (D1, D2, D3, D4, and D5) mediate all of the
physiological functions of the catecholaminergic neurotransmitter dopamine, ranging from …

G protein-coupled receptor kinases: more than just kinases and not only for GPCRs

EV Gurevich, JJG Tesmer, A Mushegian… - Pharmacology & …, 2012 - Elsevier
G protein-coupled receptor (GPCR) kinases (GRKs) are best known for their role in
homologous desensitization of GPCRs. GRKs phosphorylate activated receptors and …

Links between dietary salt intake, renal salt handling, blood pressure, and cardiovascular diseases

P Meneton, X Jeunemaitre… - Physiological …, 2005 - journals.physiology.org
Epidemiological, migration, intervention, and genetic studies in humans and animals
provide very strong evidence of a causal link between high salt intake and high blood …

Gut microbiota in hypertension

PA Jose, D Raj - Current opinion in nephrology and hypertension, 2015 - journals.lww.com
Gut microbiota in hypertension : Current Opinion in Nephrology and Hypertension Gut
microbiota in hypertension : Current Opinion in Nephrology and Hypertension Log in or …

How NaCl raises blood pressure: a new paradigm for the pathogenesis of salt-dependent hypertension

MP Blaustein, FHH Leenen, L Chen… - American Journal …, 2012 - journals.physiology.org
Excess dietary salt is a major cause of hypertension. Nevertheless, the specific mechanisms
by which salt increases arterial constriction and peripheral vascular resistance, and thereby …

Physiological roles of G protein–coupled receptor kinases and arrestins

RT Premont, RR Gainetdinov - Annu. Rev. Physiol., 2007 - annualreviews.org
Heterotrimeric G protein–coupled receptors (GPCRs) are found on the surface of all cells of
multicellular organisms and are major mediators of intercellular communication. More than …

Regulation of G protein-coupled receptor kinases and arrestins during receptor desensitization

TA Kohout, RJ Lefkowitz - Molecular pharmacology, 2003 - ASPET
With at least 1000 family members encoded by mammalian genomes, the G protein-coupled
receptors (GPCRs) represent the most diverse group of signaling proteins known (Bockaert …

The evolving impact of g protein-coupled receptor kinases in cardiac health and disease

PY Sato, JK Chuprun, M Schwartz… - Physiological …, 2015 - journals.physiology.org
G protein-coupled receptors (GPCRs) are important regulators of various cellular functions
via activation of intracellular signaling events. Active GPCR signaling is shut down by GPCR …

Genetics of hypertension in African Americans and others of African descent

M Zilbermint, F Hannah-Shmouni… - International journal of …, 2019 - mdpi.com
Hypertension is the leading cause of cardiovascular disease in the United States, affecting
up to one-third of adults. When compared to other ethnic or racial groups in the United …