Caffeic acid (CA) and its phenethyl ester (CAPE) are naturally occurring hydroxycinnamic
acids with an interesting array of biological activities; eg, antioxidant, anti-inflammatory …

Stroke is an emerging major health problem often resulting in death or disability.
Hyperlipidemia, high blood pressure and diabetes are well established risk factors …

Hydroxycinnamates are among the most widely distributed plant phenylpropanoids present
in the free, conjugated-soluble and insoluble-bound forms. This review will focus on the …

Caffeic acid phenethyl ester (CAPE), as one of the main active ingredients of the natural
product propolis, shows the unique biological activities such as anti-tumor, anti-oxidation …

Propolis is a resinous substance produced by honeybees that possesses many biological
activities, such as antitumor, antioxidant, antimicrobial, anti-inflammatory, and …

The past decades have seen a growing interest in natural products. Caffeic acid phenethyl
ester (CAPE), a flavonoid isolated from honeybee propolis, has shown multiple …

Free radicals are highly reactive molecules produced in the cell either as part of, or as end-
products of, biochemical reactions that have crucial roles in the homeostasis of the …

In this study, we evaluated the abilities of a series of chalcones to inhibit the activity of the
enzyme xanthine oxidase (XO) and to scavenge radicals. 20 mono-and polyhydroxylated …

Ischemic stroke is a neurovascular disease treatable by thrombolytic therapy, but the therapy
has to be initiated within 3 h of the incident. This therapeutic limitation stems from the …

We examined whether Brazilian green propolis, a widely used folk medicine, has a
neuroprotective function in vitro and/or in vivo. In vitro, propolis significantly inhibited …