In addition to its role in calcium homeostasis and bone formation, a modulatory role of the
active form of vitamin D on cells of the immune system, particularly T lymphocytes, has been …

Vitamin D deficiency has been associated with the risk of multiple sclerosis, disease activity
and progression. Results from in vitro experiments, animal models and analysis of human …

Regulation of immune function continues to be one of the most well recognized extraskeletal
actions of vitamin D. This stemmed initially from the discovery that antigen presenting cells …

Vitamin D exerts multiple immunomodulatory functions and has been implicated in the
etiology and treatment of several autoimmune diseases, including multiple sclerosis (MS) …

As the most common non-traumatic disabling disease among adolescents, multiple sclerosis
(MS) is a devastating neurological inflammatory disease of the central nervous system …

Dynamic, coordinated changes in metabolic pathway activity underpin the protective and
inflammatory activity of T cells, through provision of energy and biosynthetic precursors for …

The etiological complexity of multiple sclerosis, an immune-mediated, neurodegenerative
disease with multifactorial etiology is still elusive because of an incomplete understanding of …

Rheumatoid arthritis (RA) is a chronic autoimmune disorder that can give rise to joint
swelling and inflammation, potentially affecting the entire body, closely linked to the state of …

Celiac Disease (CeD) is a complex immune disorder involving villous atrophy in the small
intestine that is triggered by gluten intake. Current CeD diagnosis is based on late-stage …

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system. We review the two core MS features, myelin instability, fragmentation, and …