Improved DNA vaccine delivery with needle-free injection systems
DNA vaccines have inherent advantages compared to other vaccine types, including safety,
rapid design and construction, ease and speed to manufacture, and thermostability …
rapid design and construction, ease and speed to manufacture, and thermostability …
The development of DNA vaccines against SARS-CoV-2
Background The COVID-19 pandemic exerted significant impacts on public health and
global economy. Research efforts to develop vaccines at warp speed against SARS-CoV-2 …
global economy. Research efforts to develop vaccines at warp speed against SARS-CoV-2 …
Immunogenicity of candidate MERS-CoV DNA vaccines based on the spike protein
SS Al-Amri, AT Abbas, LA Siddiq, A Alghamdi… - Scientific reports, 2017 - nature.com
MERS-coronavirus is a novel zoonotic pathogen which spread rapidly to> 25 countries since
2012. Its apparent endemicity and the wide spread of its reservoir host (dromedary camels) …
2012. Its apparent endemicity and the wide spread of its reservoir host (dromedary camels) …
[HTML][HTML] A contemporary review on the important role of in silico approaches for managing different aspects of COVID-19 crisis
In the last century, the emergence of in silico tools has improved the quality of healthcare
studies by providing high quality predictions. In the case of COVID-19, these tools have …
studies by providing high quality predictions. In the case of COVID-19, these tools have …
Immune responses, therapeutic anti-tumor effects, and tolerability upon therapeutic HPV16/18 E6/E7 DNA vaccination via needle-free biojector
Intramuscular vaccination of mice with the naked pBI-11 DNA plasmid targeting E6 and E7
of HPV16 and HPV18 via a conventional syringe and needle generates human …
of HPV16 and HPV18 via a conventional syringe and needle generates human …
DNA based vaccine expressing SARS-CoV-2 Spike-CD40L fusion protein confers protection against challenge in a Syrian hamster model
LA Tamming, D Duque, A Tran, W Zhang… - Frontiers in …, 2022 - frontiersin.org
SARS-CoV-2 infections present a tremendous threat to public health. Safe and efficacious
vaccines are the most effective means in preventing the infections. A variety of vaccines …
vaccines are the most effective means in preventing the infections. A variety of vaccines …
SARS-CoV-2 doggybone DNA vaccine produces cross-variant neutralizing antibodies and is protective in a COVID-19 animal model
To combat the COVID-19 pandemic, an assortment of vaccines has been developed.
Nucleic acid vaccines have the advantage of rapid production, as they only require a viral …
Nucleic acid vaccines have the advantage of rapid production, as they only require a viral …
Duck CD40L as an adjuvant enhances systemic immune responses of avian flavivirus DNA vaccine
J Huang, G Luo, W Wang, Y Lu, M Wang, M Liu, D Zhu… - npj Vaccines, 2024 - nature.com
Under the dual pressure of emerging zoonoses and the difficulty in eliminating conventional
zoonoses, the strategic management of bird diseases through vaccination represents a …
zoonoses, the strategic management of bird diseases through vaccination represents a …
Mucosal SARS-CoV-2 S1 adenovirus-based vaccine elicits robust systemic and mucosal immunity and protects against disease in animals
The COVID-19 pandemic has emphasized the importance and need for accessible safe,
effective, and versatile vaccine platforms. While approved SARS-CoV-2 vaccines have been …
effective, and versatile vaccine platforms. While approved SARS-CoV-2 vaccines have been …
[HTML][HTML] Pre-existing Immunity to Endemic Human Coronaviruses Does Not Affect the Immune Response to SARS-CoV-2 Spike in a Murine Vaccination Model
AY Jeong, P Lee, MS Lee, DJ Kim - Immune Network, 2023 - ncbi.nlm.nih.gov
Endemic human coronaviruses (HCoVs) have been evidenced to be cross-reactive to
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although a correlation …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although a correlation …