Type 2 diabetes mellitus in older adults: clinical considerations and management
S Bellary, I Kyrou, JE Brown, CJ Bailey - Nature Reviews Endocrinology, 2021 - nature.com
The past 50 years have seen a growing ageing population with an increasing prevalence of
type 2 diabetes mellitus (T2DM); now, nearly half of all individuals with diabetes mellitus are …
type 2 diabetes mellitus (T2DM); now, nearly half of all individuals with diabetes mellitus are …
[HTML][HTML] Gestational diabetes mellitus-A metabolic and reproductive disorder
AA Choudhury, VD Rajeswari - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Maternal health associated with Gestational Diabetes Mellitus (GDM) has been gaining
significant research attention due to its severe risk and adverse health effects. GDM is the …
significant research attention due to its severe risk and adverse health effects. GDM is the …
Cardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of cardiovascular …
Summary Background Glucagon-like peptide-1 (GLP-1) receptor agonists differ in their
structure and duration of action and have been studied in trials of varying sizes and with …
structure and duration of action and have been studied in trials of varying sizes and with …
Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo …
AF Hernandez, JB Green, S Janmohamed… - The Lancet, 2018 - thelancet.com
Background Glucagon-like peptide 1 receptor agonists differ in chemical structure, duration
of action, and in their effects on clinical outcomes. The cardiovascular effects of once-weekly …
of action, and in their effects on clinical outcomes. The cardiovascular effects of once-weekly …
Type 2 diabetes in adolescents and young adults
N Lascar, J Brown, H Pattison, AH Barnett… - The lancet Diabetes & …, 2018 - thelancet.com
The prevalence of type 2 diabetes in adolescents and young adults is dramatically
increasing. Similar to older-onset type 2 diabetes, the major predisposing risk factors are …
increasing. Similar to older-onset type 2 diabetes, the major predisposing risk factors are …
Novel therapies with precision mechanisms for type 2 diabetes mellitus
Type 2 diabetes mellitus (T2DM) is one of the greatest health crises of our time and its
prevalence is projected to increase by> 50% globally by 2045. Currently, 10 classes of …
prevalence is projected to increase by> 50% globally by 2045. Currently, 10 classes of …
GLP-1 and the kidney: from physiology to pharmacology and outcomes in diabetes
MHA Muskiet, L Tonneijck, MM Smits… - Nature Reviews …, 2017 - nature.com
The gastrointestinal tract—the largest endocrine network in human physiology—
orchestrates signals from the external environment to maintain neural and hormonal control …
orchestrates signals from the external environment to maintain neural and hormonal control …
[HTML][HTML] Peptide therapeutics from venom: Current status and potential
MW Pennington, A Czerwinski, RS Norton - Bioorganic & medicinal …, 2018 - Elsevier
Peptides are recognized as being highly selective, potent and relatively safe as potential
therapeutics. Peptides isolated from the venom of different animals satisfy most of these …
therapeutics. Peptides isolated from the venom of different animals satisfy most of these …
[HTML][HTML] Pharmacologic management of type 2 diabetes mellitus: available therapies
J Thrasher - The American journal of cardiology, 2017 - Elsevier
Choices for the treatment of type 2 diabetes mellitus (T2DM) have multiplied as our
understanding of the underlying pathophysiologic defects has evolved. Treatment should …
understanding of the underlying pathophysiologic defects has evolved. Treatment should …
SGLT-2 inhibitors and GLP-1 receptor agonists for nephroprotection and cardioprotection in patients with diabetes mellitus and chronic kidney disease. A consensus …
Chronic kidney disease (CKD) in patients with diabetes mellitus (DM) is a major problem of
public health. Currently, many of these patients experience progression of cardiovascular …
public health. Currently, many of these patients experience progression of cardiovascular …