Stimuli-responsive microneedles as a transdermal drug delivery system: a demand-supply strategy
Microneedles are one of the most prominent approaches capable of physically disrupting
the stratum corneum without devastating the deeper tissues to deliver both small molecules …
the stratum corneum without devastating the deeper tissues to deliver both small molecules …
Thrombin: a pivotal player in hemostasis and beyond
JB Larsen, AM Hvas - Seminars in Thrombosis and Hemostasis, 2021 - thieme-connect.com
The serine protease thrombin, a naturally derived enzyme, plays a key role in hemostasis by
converting fibrinogen to fibrin and activating coagulation factor XIII whereby the fibrin clot is …
converting fibrinogen to fibrin and activating coagulation factor XIII whereby the fibrin clot is …
Role of thrombin to non-physiological shear stress induced platelet activation and function alternation
W Sun, D Han, MA Awad, JL Leibowitz, BP Griffith… - Thrombosis …, 2022 - Elsevier
Objective Non-physiological shear stress (NPSS) and thrombin have two distinct
mechanisms for activating platelets. NPSS in mechanically assisted circulation (MAC) …
mechanisms for activating platelets. NPSS in mechanically assisted circulation (MAC) …
Association of Global Coagulation Profiles With Cardiovascular Risk Factors and Atherosclerosis: A Sex Disaggregated Analysis From the BioHEART‐CT Study
KA Kott, MC Morel‐Kopp, ST Vernon… - Journal of the …, 2021 - Am Heart Assoc
Background Although the association between dysregulated coagulation and
atherosclerosis is well recognized, individual assays have been of minimal value in …
atherosclerosis is well recognized, individual assays have been of minimal value in …
Endogenous thrombin potential and time-dependent thrombin generation parameters are independent risk factors for mortality in the general population
Background Thrombin generation (TG) is used as a global test of coagulation and is an
indicator of thrombosis and bleeding risk. Until now, data on the association of TG and …
indicator of thrombosis and bleeding risk. Until now, data on the association of TG and …
Unraveling the crosstalk between renin‐angiotensin system receptors
MM Gironacci, E Bruna‐Haupt - Acta Physiologica, 2024 - Wiley Online Library
The renin‐angiotensin system (RAS) plays a key role in blood pressure regulation. The RAS
is a complex interconnected system composed of two axes with opposite effects. The …
is a complex interconnected system composed of two axes with opposite effects. The …
Prognostic Factors for Restenosis of Superficial Femoral Artery after Endovascular Treatment
V Boc, M Kozak, B Eržen, M Božič Mijovski… - Journal of Clinical …, 2023 - mdpi.com
High incidence of superficial femoral artery (SFA) restenosis after percutaneous transluminal
angioplasty (PTA) poses a persistent challenge in peripheral arterial disease (PAD) …
angioplasty (PTA) poses a persistent challenge in peripheral arterial disease (PAD) …
Activated Partial Thromboplastin Time-based Clot Waveform Analysis: A Potential for Application in Acute Myocardial Infarction and Its Complications
FMR Uy, CL Ng, MA Cheong, WH Wong… - Available at SSRN …, 2023 - papers.ssrn.com
Background: Activated partial thromboplastin time (aPTT)-based clot waveform analysis
(CWA) is a plasma-based global haemostatic assay. Elevated CWA parameters have been …
(CWA) is a plasma-based global haemostatic assay. Elevated CWA parameters have been …