Parkinson's disease (PD) is the second most predominant neurodegenerative disease
worldwide. It is recognized clinically by severe complications in motor function caused by …

Parkinson disease (PD) is characterized by loss of the A9 nigral neurons that provide
dopaminergic innervation to the striatum. This discovery led to the successful instigation of …

Induced pluripotent stem cells (iPS cells) are a promising source for a cell-based therapy to
treat Parkinson's disease (PD), in which midbrain dopaminergic neurons progressively …

Cell replacement therapies for Parkinson's disease (PD) based on transplantation of
pluripotent stem cell-derived dopaminergic neurons are now entering clinical trials. Here, we …

Autologous transplantation of patient-specific induced pluripotent stem cell (iPSC)-derived
neurons is a potential clinical approach for treatment of neurological disease. Preclinical …

Degeneration of dopamine (DA) neurons in the midbrain underlies the pathogenesis of
Parkinson's disease (PD). Supplement of DA via L-DOPA alleviates motor symptoms but …

Parkinson's disease (PD) is the second most prevalent neurological disorder and has been
the focus of intense investigations to understand its etiology and progression, but it still lacks …

Pluripotent stem cells have the ability to undergo self‐renewal and to give rise to all cells of
the tissues of the body. However, this definition has been recently complicated by the …

A variety of neurological disorders are attractive targets for stem and progenitor cell-based
therapy. Yet many conditions are not, whether by virtue of an inhospitable disease …

Aging causes many changes in the human body, and is a high risk for various diseases.
Dementia, a common age-related disease, is a clinical disorder triggered by …