In many asthmatics, chronic airway inflammation is driven by IL-4-, IL-5-, and IL-13-
producing Th2 cells or ILC2s. Type 2 cytokines promote hallmark features of the disease …

More than a decade ago, type 2 innate lymphoid cells (ILC2s) were discovered to be
members of a family of innate immune cells consisting of five subsets that form a first line of …

Tissue-resident innate lymphoid cells (ILCs) help sustain barrier function and respond to
local signals. ILCs are traditionally classified as ILC1, ILC2 or ILC3 on the basis of their …

Innate lymphoid cells (ILCs) participate in tissue homeostasis, inflammation, and early
immunity against infection. It is unclear how ILCs acquire effector function and whether these …

Type 2 immunity is orchestrated by a canonical group of cytokines primarily produced by
innate lymphoid cells, group 2, and their adaptive counterparts, CD4+ helper type 2 cells …

The structural properties of biomaterials play crucial roles in guiding cell behavior and
influencing immune responses against the material. We fabricated electrospun membranes …

INTRODUCTION The predominant sites where hematopoiesis occurs change during the
course of mammalian development. Bone marrow (BM) hematopoiesis has long been …

Natural killer (NK) cells are present in the circulation and can also be found residing in
tissues, and these populations exhibit distinct developmental requirements and are thought …

Innate lymphoid cells (ILC) are abundant in mucosal tissues. They serve critical functions in
anti-pathogen response and tissue homeostasis. However, the heterogenous composition of …

Allergic immunity is orchestrated by group 2 innate lymphoid cells (ILC2s) and type 2 helper
T (Th2) cells prominently arrayed at epithelial-and microbial-rich barriers. However, ILC2s …