Recognizing the importance of childhood maltreatment as a critical factor in psychiatric diagnoses, treatment, research, prevention, and education
MH Teicher, JB Gordon, CB Nemeroff - Molecular psychiatry, 2022 - nature.com
Childhood maltreatment is the most important preventable risk factor for psychiatric
disorders. Maltreated individuals typically develop psychiatric disorders at an earlier age …
disorders. Maltreated individuals typically develop psychiatric disorders at an earlier age …
Diet, stress and mental health
Introduction: There has long been an interest in the effects of diet on mental health, and the
interaction of the two with stress; however, the nature of these relationships is not well …
interaction of the two with stress; however, the nature of these relationships is not well …
The devastating clinical consequences of child abuse and neglect: increased disease vulnerability and poor treatment response in mood disorders
ETC Lippard, CB Nemeroff - American journal of psychiatry, 2020 - Am Psychiatric Assoc
A large body of evidence has demonstrated that exposure to childhood maltreatment at any
stage of development can have long-lasting consequences. It is associated with a marked …
stage of development can have long-lasting consequences. It is associated with a marked …
Prevalence of low-grade inflammation in depression: a systematic review and meta-analysis of CRP levels
BackgroundPeripheral low-grade inflammation in depression is increasingly seen as a
therapeutic target. We aimed to establish the prevalence of low-grade inflammation in …
therapeutic target. We aimed to establish the prevalence of low-grade inflammation in …
Developmental trajectories of early life stress and trauma: a narrative review on neurobiological aspects beyond stress system dysregulation
Early life stressors display a high universal prevalence and constitute a major public health
problem. Prolonged psychoneurobiological alterations as sequelae of early life stress (ELS) …
problem. Prolonged psychoneurobiological alterations as sequelae of early life stress (ELS) …
Immunoneuropsychiatry—novel perspectives on brain disorders
Immune processes have a vital role in CNS homeostasis, resilience and brain reserve. Our
cognitive and social abilities rely on a highly sensitive and fine-tuned equilibrium of immune …
cognitive and social abilities rely on a highly sensitive and fine-tuned equilibrium of immune …
Genes, environments, and time: the biology of adversity and resilience
Exposures to adverse environments, both psychosocial and physicochemical, are prevalent
and consequential across a broad range of childhood populations. Such adversity …
and consequential across a broad range of childhood populations. Such adversity …
Annual Research Review: Suicide among youth–epidemiology,(potential) etiology, and treatment
Background Suicide is a leading cause of death and a complex clinical outcome. Here, we
summarize the current state of research pertaining to suicidal thoughts and behaviors in …
summarize the current state of research pertaining to suicidal thoughts and behaviors in …
[HTML][HTML] Adverse childhood experiences and life opportunities: Shifting the narrative
M Metzler, MT Merrick, J Klevens, KA Ports… - Children and youth …, 2017 - Elsevier
Substantial research shows that early adversity, including child abuse and neglect, is
associated with diminished health across the life course and across generations. Less well …
associated with diminished health across the life course and across generations. Less well …
Childhood and adolescent adversity and cardiometabolic outcomes: a scientific statement from the American Heart Association
Adverse experiences in childhood and adolescence, defined as subjectively perceived
threats to the safety or security of the child's bodily integrity, family, or social structures, are …
threats to the safety or security of the child's bodily integrity, family, or social structures, are …