A unifying feature of solid tumors is a markedly altered pH profile compared to normal
tissues. This reflects that solid tumors, despite completely different origins, often share …

Background In this study, we retrospectively summarized the differences of molecular gene
mutations between MDS and AML patients, as well as the young and older age groups of …

Pediatric myelodysplastic syndromes (MDS) are a heterogeneous disease group associated
with impaired hematopoiesis, bone marrow hypocellularity, and frequently have deletions …

The DNA damage response enables cells to survive and maintain genome integrity. RAD52
is a DNA-binding protein involved in the homologous recombination in DNA repair, and is …

Some studies show that alterations in DNA repair genes polymorphisms are associated with
the pathogenesis and susceptibility of Myelodysplastic Syndrome (MDS). We genotyped 60 …

Background: One of the factors that contribute to Alzheimer's disease (AD) is the DNA
damage caused by oxidative stress and inflammation that occurs in nerve cells. It has been …

Abstract Background Radiation sensitive 52 (RAD52) is an important protein that mediates
DNA repair in tumors. However, little is known about the impact of RAD52 on hepatocellular …

The goal of this study was to explore the plasma proteome of myelodysplastic syndrome
(MDS) patients with refractory anemia with excess blasts subtype 2 (RAEB‐2) in comparison …

Myelodysplastic syndromes (MDSs) are heterogeneous hematopoietic disease
characterized by ineffective haematopoiesis that frequently transforms into acute leukaemia …

Background The high incidence of mutations and cytogenetic abnormalities in patients with
myelodysplastic syndrome (MDS) suggests that defects in DNA repair mechanisms. We …