The study of an organism's response to cerebral ischemia at different levels is essential to
understanding the mechanism of the injury and protection. A great interest is devoted to …

Objective Brain proton (1 H) magnetic resonance spectroscopy (MRS) lactate/N-
acetylaspartate (Lac/NAA) peak area ratio is used for prognostication in neonatal …

An acute reduction in plasma osmolality causes rapid uptake of water by astrocytes but not
by neurons, whereas both cell types swell as a consequence of lost blood flow (ischemia) …

Background: Metabolomics—the novel science that evaluates the multitude of low-molecular-
weight metabolites in a biological system, provides new data on pathogenic mechanisms of …

Background The time course of cellular damage after acute ischemic stroke (IS) is currently
not well known, and specific noninvasive markers of microstructural alterations linked to …

Our pilot study suggested that orally administered crocin was hardly absorbed into
circulatory system, but it was effective against cerebral ischemic/reperfusion (I/R) injury. The …

Despite therapeutic hypothermia, survivors of neonatal encephalopathy have high rates of
adverse outcome. Early surrogate outcome measures are needed to speed up the …

Abstract Background Buyang Huanwu Decoction (BYHWD) is a Traditional Chinese
Medicine (TCM) formula for treating stroke-induced disability. Xiaoshuan enteric-coated …

Despite the prevalence of migraine, the pathophysiology of the disease remains unclear.
Current understanding of migraine has alluded to the possibility of a hyperexcitable brain …

Therapeutic hypothermia does not improve outcomes in neonatal hypoxia ischemia (HI)
complicated by perinatal infection, due to well-described, pre-existing oxidative stress and …