The mechanism of action of interferon-β in relapsing multiple sclerosis
BC Kieseier - CNS drugs, 2011 - Springer
Multiple sclerosis (MS) is characterized by autoimmune inflammation and subsequent
neurodegeneration. It is believed that early in the disease course, proinflammatory T cells …
neurodegeneration. It is believed that early in the disease course, proinflammatory T cells …
Subcutaneous Recombinant Interferon-β-1a (Rebif®) A Review of its Use in the Treatment of Relapsing Multiple Sclerosis
M Sanford, KA Lyseng-Williamson - Drugs, 2011 - Springer
Subcutaneous recombinant interferon-β-1a (SC IFNβ-1a)[Rebif®] is indicated as
monotherapy for the prevention of relapses and progression of physical disability in patients …
monotherapy for the prevention of relapses and progression of physical disability in patients …
'Neuroinflammation'differs categorically from inflammation: transcriptomes of Alzheimer's disease, Parkinson's disease, schizophrenia and inflammatory diseases …
Abstract 'Neuroinflammation'has become a widely applied term in the basic and clinical
neurosciences but there is no generally accepted neuropathological tissue correlate …
neurosciences but there is no generally accepted neuropathological tissue correlate …
Gene expression profiling in multiple sclerosis: a disease of the central nervous system, but with relapses triggered in the periphery?
The aetiology of multiple sclerosis (MS), an autoimmune demyelinating disease of the
central nervous system (CNS), includes both genetic and environmental factors, but the …
central nervous system (CNS), includes both genetic and environmental factors, but the …
Identification of potential regulatory long non-coding RNA-associated competing endogenous RNA axes in periplaque regions in multiple sclerosis
H Sabaie, S Khorami Rouz, G Kouchakali… - Frontiers in …, 2022 - frontiersin.org
Slow-burning inflammation at the lesion rim is connected to the expansion of chronic
multiple sclerosis (MS) lesions. However, the underlying processes causing expansion are …
multiple sclerosis (MS) lesions. However, the underlying processes causing expansion are …
Excessive biologic response to IFNβ is associated with poor treatment response in patients with multiple sclerosis
Background Interferon-beta (IFNβ) is used to inhibit disease activity in multiple sclerosis
(MS), but its mechanisms of action are incompletely understood, individual treatment …
(MS), but its mechanisms of action are incompletely understood, individual treatment …
Acetaminophen modulates the transcriptional response to recombinant interferon-β
A Farnsworth, AS Flaman, SS Prasad, C Gravel… - PLoS …, 2010 - journals.plos.org
Background Recombinant interferon treatment can result in several common side effects
including fever and injection-site pain. Patients are often advised to use acetaminophen or …
including fever and injection-site pain. Patients are often advised to use acetaminophen or …
Gene expression in IFNss signalling pathway differs between monocytes, CD4 and CD8 T cells from MS patients
B Oliver-Martos, T Orpez, MJ Pinto-Medel… - Journal of …, 2011 - Elsevier
IFNß exerts its activity through the interaction with IFNAR, through activation of the JAK/STAT
pathway. We analyzed the changes in IFNAR1, IFNAR2, STAT1, STAT2, Tyk2, JAK1, IRF9 …
pathway. We analyzed the changes in IFNAR1, IFNAR2, STAT1, STAT2, Tyk2, JAK1, IRF9 …
Down-regulation of RORA gene expression in the blood of multiple sclerosis patients
Multiple sclerosis (MS) is an autoimmune disease characterized by recurrent episodes of
demyelination and loss of oligodendrocytes. The demyelination process is caused by …
demyelination and loss of oligodendrocytes. The demyelination process is caused by …
用于干细胞培养和治疗的培养基, 方法, 细胞和分泌的因子
阿林， 鲁思， 托马斯 - 2019 - Google Patents
CN109219658A - 用于干细胞培养和治疗的培养基,方法,细胞和分泌的因子- Google Patents
CN109219658A - 用于干细胞培养和治疗的培养基,方法,细胞和分泌的因子- Google Patents 用于 …
CN109219658A - 用于干细胞培养和治疗的培养基,方法,细胞和分泌的因子- Google Patents 用于 …