Cardiovascular risks associated with gender and aging

JL Rodgers, J Jones, SI Bolleddu… - Journal of …, 2019 - mdpi.com
The aging and elderly population are particularly susceptible to cardiovascular disease. Age
is an independent risk factor for cardiovascular disease (CVD) in adults, but these risks are …

The role of testosterone in the elderly: what do we know?

B Barone, L Napolitano, M Abate, L Cirillo… - International journal of …, 2022 - mdpi.com
Testosterone is the most important hormone in male health. Aging is characterized by
testosterone deficiency due to decreasing testosterone levels associated with low testicular …

Testosterone replacement therapy and cardiovascular risk

T Gagliano-Jucá, S Basaria - Nature Reviews Cardiology, 2019 - nature.com
Testosterone is the main male sex hormone and is essential for the maintenance of male
secondary sexual characteristics and fertility. Androgen deficiency in young men owing to …

The role of adiponectin in cancer: a review of current evidence

M Dalamaga, KN Diakopoulos… - Endocrine …, 2012 - academic.oup.com
Improving physical function and mobility in a continuously expanding elderly population
emerges as a high priority of medicine today. Muscle mass, strength/power, and maximal …

Sex differences in vascular physiology and pathophysiology: estrogen and androgen signaling in health and disease

AC Boese, SC Kim, KJ Yin, JP Lee… - American Journal of …, 2017 - journals.physiology.org
Sex differences between women and men are often overlooked and underappreciated when
studying the cardiovascular system. It has been long assumed that men and women are …

Hypogonadism as a risk factor for cardiovascular mortality in men: a meta-analytic study

G Corona, G Rastrelli, M Monami… - European journal of …, 2011 - academic.oup.com
Objective To verify whether hypogonadism represents a risk factor for cardiovascular (CV)
morbidity and mortality and to verify whether testosterone replacement therapy (TRT) …

Testosterone therapy and cardiovascular risk: advances and controversies

A Morgentaler, MM Miner, M Caliber, AT Guay… - Mayo Clinic …, 2015 - Elsevier
Two recent studies raised new concerns regarding cardiovascular (CV) risks with
testosterone (T) therapy. This article reviews those studies as well as the extensive literature …

[HTML][HTML] Sex differences in the blood–brain barrier: implications for mental health

L Dion-Albert, LB Binder, B Daigle, A Hong-Minh… - Frontiers in …, 2022 - Elsevier
Prevalence of mental disorders, including major depressive disorder (MDD), bipolar
disorder (BD) and schizophrenia (SZ) are increasing at alarming rates in our societies …

High serum testosterone is associated with reduced risk of cardiovascular events in elderly men: the MrOS (Osteoporotic Fractures in Men) study in Sweden

C Ohlsson, E Barrett-Connor, S Bhasin, E Orwoll… - Journal of the American …, 2011 - jacc.org
Objectives: We tested the hypothesis that serum total testosterone and sex hormone–
binding globulin (SHBG) levels predict cardiovascular (CV) events in community-dwelling …

Sex differences in stroke: review of current knowledge and evidence

RL Girijala, F Sohrabji, RL Bush - Vascular medicine, 2017 - journals.sagepub.com
Stroke is a leading cause of death among women in the United States, and women are more
affected by stroke than men. With women living longer than men, women experience not …