C-reactive protein (CRP) is routinely assessed as a marker of systemic inflammation in
rheumatoid arthritis (RA). However, it is also an immune regulator that plays an important …

Nucleic acid aptamers capable of affine and specific binding to their molecular targets have
now established themselves as a very promising alternative to monoclonal antibodies for …

Osteogenesis in human arterial smooth muscle cell (HASMC) is a key feature of uremic
vascular calcification (UVC). Concerning pro-oxidant properties of p-cresyl sulfate (PCS), the …

We formerly proved that uremic vascular calcification (UVC) correlates tightly with oxidative
elastic lamina (EL) injury and two cell fates (apoptosis and osteocytic conversion) in smooth …

Background: Uremic vascular calcification (UVC) is reminiscent of osteogenesis and
apoptosis in vascular smooth muscle cell (VSMC). We aimed to identify how circulating …

Relevance. Non-steroidal anti-inflammatory drugs are among the top requested ones in the
clinic of internal medicine. However, these drugs are associated with a wide range of …

Acute coronary syndrome (ACS) is the main manifestation of cardiovascular disease and the
primary cause of adult hospitalization in China. There is an urgent demand for novel …

Patients with chronic kidney disease (CKD), especially those undergoing hemodialysis, are
at a considerably high risk of bone fracture events. Experimental data indicate that uremic …

Objective: Systemic hypoperfusion is intricately involved in neurohormone secretion,
vascular calcification (VC) related impaired vasodilation, and luminal stenosis. We aimed to …

Актуальность. Нестероидные противовоспалительные препараты являются одними из
наиболее востребованных классов лекарственных средств в клинике внутренней …