[HTML][HTML] Histopathological findings and clinicopathologic correlation in COVID-19: a systematic review

S Caramaschi, ME Kapp, SE Miller, R Eisenberg… - Modern Pathology, 2021 - Elsevier
The severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) pandemic has had
devastating effects on global health and worldwide economy. Despite an initial reluctance to …

[HTML][HTML] Molecular dynamics of lipopolysaccharide-induced lung injury in rodents

H Domscheit, MA Hegeman, N Carvalho… - Frontiers in …, 2020 - frontiersin.org
Acute respiratory distress syndrome (ARDS) is a common disease entity in critical care
medicine and is still associated with a high mortality. Because of the heterogeneous …

Acute respiratory distress syndrome as an organ phenotype of vascular microthrombotic disease: based on hemostatic theory and endothelial molecular pathogenesis

JC Chang - Clinical and Applied Thrombosis/Hemostasis, 2019 - journals.sagepub.com
Acute respiratory distress syndrome (ARDS) is a life-threatening noncardiogenic circulatory
disorder of the lungs associated with critical illnesses such as sepsis, trauma, and immune …

Activation of NLRP3 inflammasome in alveolar macrophages contributes to mechanical stretch-induced lung inflammation and injury

J Wu, Z Yan, DE Schwartz, J Yu, AB Malik… - The Journal of …, 2013 - journals.aai.org
Mechanical ventilation of lungs is capable of activating the innate immune system and
inducing sterile inflammatory response. The proinflammatory cytokine IL-1β is among the …

[HTML][HTML] Extracorporeal organ support (ECOS) in critical illness and acute kidney injury: from native to artificial organ crosstalk

F Husain-Syed, Z Ricci, D Brodie, JL Vincent… - Intensive care …, 2018 - Springer
The complex nature of single organ failure potentially leading to multiple organ dysfunction
syndrome (MODS) in critically ill patients necessitates integrated supportive therapy. Rather …

[HTML][HTML] Curcumin modulates the inflammatory response and inhibits subsequent fibrosis in a mouse model of viral-induced acute respiratory distress syndrome

S Avasarala, F Zhang, G Liu, R Wang, SD London… - PloS one, 2013 - journals.plos.org
Acute Respiratory Distress Syndrome (ARDS) is a clinical syndrome characterized by diffuse
alveolar damage usually secondary to an intense host inflammatory response of the lung to …

Conservative oxygen therapy in mechanically ventilated patients: a pilot before-and-after trial

S Suzuki, GM Eastwood, NJ Glassford, L Peck… - Critical care …, 2014 - journals.lww.com
Objectives: To assess the feasibility and safety of a conservative approach to oxygen
therapy in mechanically ventilated ICU patients. Design: Pilot prospective before-and-after …

Interrelationship among common medical complications after acute stroke: pneumonia plays an important role

R Ji, D Wang, H Shen, Y Pan, G Liu, P Wang, Y Wang… - Stroke, 2013 - Am Heart Assoc
Background and Purpose—Medical complications are common among patients with stroke.
However, little is known about the potential interrelationship among them. In the present …

Integrative “omic” analysis of experimental bacteremia identifies a metabolic signature that distinguishes human sepsis from systemic inflammatory response …

RJ Langley, JL Tipper, S Bruse, RM Baron… - American journal of …, 2014 - atsjournals.org
Rationale: Sepsis is a leading cause of morbidity and mortality. Currently, early diagnosis
and the progression of the disease are difficult to make. The integration of metabolomic and …

Fibroproliferative changes on high-resolution CT in the acute respiratory distress syndrome predict mortality and ventilator dependency: a prospective observational …

K Ichikado, H Muranaka, Y Gushima, T Kotani… - BMJ open, 2012 - bmjopen.bmj.com
Objectives To examine whether the extent of fibroproliferative changes on high-resolution
CT (HRCT) scan influences prognosis, ventilator dependency and the associated outcomes …