Pharmaceutical cocrystals, salts and polymorphs: Advanced characterization techniques

E Pindelska, A Sokal, W Kolodziejski - Advanced drug delivery reviews, 2017 - Elsevier
The main goal of a novel drug development is to obtain it with optimal physiochemical,
pharmaceutical and biological properties. Pharmaceutical companies and scientists modify …

Citric acid: A multifunctional pharmaceutical excipient

M Lambros, T Tran, Q Fei, M Nicolaou - Pharmaceutics, 2022 - mdpi.com
Citric acid, a tricarboxylic acid, has found wide application in the chemical and
pharmaceutical industry due to its biocompatibility, versatility, and green, environmentally …

Rational coformer or solvent selection for pharmaceutical cocrystallization or desolvation

YA Abramov, C Loschen, A Klamt - Journal of pharmaceutical sciences, 2012 - Elsevier
It is demonstrated that the fluid-phase thermodynamics theory conductor-like screening
model for real solvents (COSMO-RS) as implemented in the COSMOtherm software can be …

Knowledge-based approaches to co-crystal design

PA Wood, N Feeder, M Furlow, PTA Galek… - …, 2014 - pubs.rsc.org
The use of knowledge-based methods has been intimately connected with the field of co-
crystal design since the seminal papers of Etter and Desiraju in the 1990s. Here we explain …

Adsorption of paraquat by poly (vinyl alcohol)-cyclodextrin nanosponges

E Martwong, S Chuetor, J Junthip - Polymers, 2021 - mdpi.com
The contamination of hydrosoluble pesticides in water could generate a serious problem for
biotic and abiotic components. The removal of a hazardous agrochemical (paraquat) from …

Functional materials based on molecules with hydrogen-bonding ability: applications to drug co-crystals and polymer complexes

KM Hutchins - Royal Society open science, 2018 - royalsocietypublishing.org
The design, synthesis and property characterization of new functional materials has
garnered interest in a variety of fields. Materials that are capable of recognizing and binding …

Physicochemical and mechanical properties of paracetamol cocrystal with 5-nitroisophthalic acid

S Hiendrawan, B Veriansyah, E Widjojokusumo… - International journal of …, 2016 - Elsevier
We report novel pharmaceutical cocrystal of a popular antipyretic drug paracetamol (PCA)
with coformer 5-nitroisophhthalic acid (5NIP) to improve its tabletability. The cocrystal (PCA …

Levofloxacin cocrystal/salt with phthalimide and caffeic acid as promising solid-state approach to improve antimicrobial efficiency

NU Islam, MN Umar, E Khan, FA Al-Joufi, SN Abed… - Antibiotics, 2022 - mdpi.com
To overcome the issue of multidrug resistant (MDR) microbes, the exploration of ways to
improve the antimicrobial efficiency of existing antibiotics is one of the promising …

Cocrystal systems of pharmaceutical interest: 2011

HG Brittain - Crystal growth & design, 2012 - ACS Publications
The literature published during 2011 whose subject matter encompasses the
cocrystallization of organic compounds having particular interest to pharmaceutical …

Isostructural multicomponent gliclazide crystals with improved solubility

O Dwichandra Putra, E Yonemochi… - Crystal Growth & …, 2016 - ACS Publications
This study focused on pharmaceutical isostructural multicomponent crystals and compared
their physicochemical properties. Gliclazide (GLI), a drug used for treating diabetes mellitus …