Pharmaceutical cocrystals, salts and polymorphs: Advanced characterization techniques
E Pindelska, A Sokal, W Kolodziejski - Advanced drug delivery reviews, 2017 - Elsevier
The main goal of a novel drug development is to obtain it with optimal physiochemical,
pharmaceutical and biological properties. Pharmaceutical companies and scientists modify …
pharmaceutical and biological properties. Pharmaceutical companies and scientists modify …
Citric acid: A multifunctional pharmaceutical excipient
M Lambros, T Tran, Q Fei, M Nicolaou - Pharmaceutics, 2022 - mdpi.com
Citric acid, a tricarboxylic acid, has found wide application in the chemical and
pharmaceutical industry due to its biocompatibility, versatility, and green, environmentally …
pharmaceutical industry due to its biocompatibility, versatility, and green, environmentally …
Rational coformer or solvent selection for pharmaceutical cocrystallization or desolvation
It is demonstrated that the fluid-phase thermodynamics theory conductor-like screening
model for real solvents (COSMO-RS) as implemented in the COSMOtherm software can be …
model for real solvents (COSMO-RS) as implemented in the COSMOtherm software can be …
Knowledge-based approaches to co-crystal design
PA Wood, N Feeder, M Furlow, PTA Galek… - …, 2014 - pubs.rsc.org
The use of knowledge-based methods has been intimately connected with the field of co-
crystal design since the seminal papers of Etter and Desiraju in the 1990s. Here we explain …
crystal design since the seminal papers of Etter and Desiraju in the 1990s. Here we explain …
Adsorption of paraquat by poly (vinyl alcohol)-cyclodextrin nanosponges
The contamination of hydrosoluble pesticides in water could generate a serious problem for
biotic and abiotic components. The removal of a hazardous agrochemical (paraquat) from …
biotic and abiotic components. The removal of a hazardous agrochemical (paraquat) from …
Functional materials based on molecules with hydrogen-bonding ability: applications to drug co-crystals and polymer complexes
KM Hutchins - Royal Society open science, 2018 - royalsocietypublishing.org
The design, synthesis and property characterization of new functional materials has
garnered interest in a variety of fields. Materials that are capable of recognizing and binding …
garnered interest in a variety of fields. Materials that are capable of recognizing and binding …
Physicochemical and mechanical properties of paracetamol cocrystal with 5-nitroisophthalic acid
S Hiendrawan, B Veriansyah, E Widjojokusumo… - International journal of …, 2016 - Elsevier
We report novel pharmaceutical cocrystal of a popular antipyretic drug paracetamol (PCA)
with coformer 5-nitroisophhthalic acid (5NIP) to improve its tabletability. The cocrystal (PCA …
with coformer 5-nitroisophhthalic acid (5NIP) to improve its tabletability. The cocrystal (PCA …
Levofloxacin cocrystal/salt with phthalimide and caffeic acid as promising solid-state approach to improve antimicrobial efficiency
To overcome the issue of multidrug resistant (MDR) microbes, the exploration of ways to
improve the antimicrobial efficiency of existing antibiotics is one of the promising …
improve the antimicrobial efficiency of existing antibiotics is one of the promising …
Cocrystal systems of pharmaceutical interest: 2011
HG Brittain - Crystal growth & design, 2012 - ACS Publications
The literature published during 2011 whose subject matter encompasses the
cocrystallization of organic compounds having particular interest to pharmaceutical …
cocrystallization of organic compounds having particular interest to pharmaceutical …
Isostructural multicomponent gliclazide crystals with improved solubility
O Dwichandra Putra, E Yonemochi… - Crystal Growth & …, 2016 - ACS Publications
This study focused on pharmaceutical isostructural multicomponent crystals and compared
their physicochemical properties. Gliclazide (GLI), a drug used for treating diabetes mellitus …
their physicochemical properties. Gliclazide (GLI), a drug used for treating diabetes mellitus …