Endothelial cell-derived TGF-β promotes epithelial-mesenchymal transition via CD133 in HBx-infected hepatoma cells

P Rawal, H Siddiqui, M Hassan, MC Choudhary… - Frontiers in …, 2019 - frontiersin.org
Background: Hepatitis BX Protein (HBx) encoded in Hepatitis B virus (HBV) is known to play
a critical role in development and progression of HBV induced hepatocellular carcinoma …

Melatonin modulates the Warburg effect and alters the morphology of hepatocellular carcinoma cell line resulting in reduced viability and migratory potential

EMS Cruz, VM Concato, JMB de Morais, TF Silva… - Life Sciences, 2023 - Elsevier
Abstract Aims Hepatocellular Carcinoma (HCC) is a primary neoplasm derived from
hepatocytes with low responsiveness and recurrent chemoresistance. Melatonin is an …

Clinical significance of C/D box small nucleolar RNA U76 as an oncogene and a prognostic biomarker in hepatocellular carcinoma

L Wu, L Chang, H Wang, W Ma, Q Peng… - Clinics and Research in …, 2018 - Elsevier
Background Recent evidence has suggested novel roles of small nucleolar RNAs
(snoRNAs) in tumorigenicity. However, the roles of C/D box snoRNA U76 (SNORD76) in the …

Downregulation of PDGF-D inhibits proliferation and invasion in breast cancer MDA-MB-231 cells

JF Lu, ZQ Hu, MX Yang, WY Liu, GF Pan, JB Ding… - Clinical Breast …, 2022 - Elsevier
Background The platelet derived growth factor-D (PDGF-D) plays an important role in breast
tumor aggressiveness. However, limited study has investigated the effect of silencing PDGF …

Unconventional MAPK-GSK-3β Pathway Behind Atypical Epithelial-Mesenchymal Transition In Hepatocellular Carcinoma

S Parveen, D Vedagiri, HG Nair, H Parthasarathy… - Scientific reports, 2017 - nature.com
We recently reported an atypical epithelial mesenchymal transition (EMT) in human
hepatoma cell culture Huh7. 5, which was non-responsive to the canonical EMT …