Role of m6A writers, erasers and readers in cancer

Z Fang, W Mei, C Qu, J Lu, L Shang, F Cao… - … Hematology & Oncology, 2022 - Springer
Abstract The N (6)-methyladenosine (m6A) modification is the most pervasive modification of
human RNAs. In recent years, an increasing number of studies have suggested that m6A …

MicroRNA let-7 and viral infections: focus on mechanisms of action

A Letafati, S Najafi, M Mottahedi, M Karimzadeh… - Cellular & Molecular …, 2022 - Springer
MicroRNAs (miRNAs) are fundamental post-transcriptional modulators of several critical
cellular processes, a number of which are involved in host defense mechanisms. In …

IGF2BP3 from physiology to cancer: novel discoveries, unsolved issues, and future perspectives

C Mancarella, K Scotlandi - Frontiers in cell and developmental …, 2020 - frontiersin.org
RNA network control is a key aspect of proper cellular homeostasis. In this context, RNA-
binding proteins (RBPs) play a major role as regulators of the RNA life cycle due to their …

[HTML][HTML] CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis

W Zhang, H Liu, J Jiang, Y Yang, W Wang… - Aging (Albany NY …, 2021 - ncbi.nlm.nih.gov
Metastasis is the leading cause of breast cancer (BC)-related deaths. Circular RNAs
(circRNAs) have emerged as essential regulators for cancer progression and metastasis …

Innate and adaptive γδ T cells: How, when, and why

M Papadopoulou, G Sanchez Sanchez… - Immunological …, 2020 - Wiley Online Library
Summary γδ T cells comprise the third cell lineage of lymphocytes that use, like αβ T cells
and B cells, V (D) J gene rearrangement with the potential to generate a highly diverse T cell …

The biological function of IGF2BPs and their role in tumorigenesis

QY Du, ZM Zhu, DS Pei - Investigational new drugs, 2021 - Springer
The insulin-like growth factor-2 mRNA-binding proteins (IGF2BPs) pertain to a highly
conservative RNA-binding family that works as a post-transcriptional fine-tuner for target …

CRISPR/Cas9 application in cancer therapy: a pioneering genome editing tool

S Shojaei Baghini, ZR Gardanova, SAH Abadi… - Cellular & Molecular …, 2022 - Springer
The progress of genetic engineering in the 1970s brought about a paradigm shift in genome
editing technology. The clustered regularly interspaced short palindromic repeats/CRISPR …

LIN28B-AS1-IGF2BP1 binding promotes hepatocellular carcinoma cell progression

J Zhang, K Hu, Y Yang, Y Wang, Y Zheng, Y Jin… - Cell Death & …, 2020 - nature.com
IGF2BP1 overexpression promotes hepatocellular carcinoma (HCC) progression. Long non-
coding RNA LIN28B-AS1 directly binds to IGF2BP1. In the present study, LIN28B-AS1 and …

[HTML][HTML] IGF2BPs as novel m6A readers: Diverse roles in regulating cancer cell biological functions, hypoxia adaptation, metabolism, and immunosuppressive tumor …

M Duan, H Liu, S Xu, Z Yang, F Zhang, G Wang… - Genes & diseases, 2024 - Elsevier
Abstract m 6 A methylation is the most frequent modification of mRNA in eukaryotes and
plays a crucial role in cancer progression by regulating biological functions. Insulin-like …

Transcriptomic profile of leg muscle during early growth in chicken

Q Xue, G Zhang, T Li, J Ling, X Zhang, J Wang - PLoS One, 2017 - journals.plos.org
The early growth pattern, especially the age of peak growth, of broilers affects the time to
market and slaughter weight, which in turn affect the profitability of the poultry industry …