The effects of early-life iron deficiency on brain energy metabolism

TW Bastian, R Rao, PV Tran… - Neuroscience …, 2020 - journals.sagepub.com
Iron deficiency (ID) is one of the most prevalent nutritional deficiencies in the world. Iron
deficiency in the late fetal and newborn period causes abnormal cognitive performance and …

Striking while the iron is hot: understanding the biological and neurodevelopmental effects of iron deficiency to optimize intervention in early childhood

JR Doom, MK Georgieff - Current pediatrics reports, 2014 - Springer
Prenatal and early postnatal iron deficiency (ID) is associated with long-term neurobiological
alterations and disruptions in cognitive, social, and behavioral development. Early life ID is …

Fetal iron deficiency induces chromatin remodeling at the Bdnf locus in adult rat hippocampus

PV Tran, BC Kennedy, YC Lien… - American Journal …, 2015 - journals.physiology.org
Fetal and subsequent early postnatal iron deficiency causes persistent impairments in
cognitive and affective behaviors despite prompt postnatal iron repletion. The long-term …

[HTML][HTML] Prenatal choline supplementation diminishes early-life iron deficiency–induced reprogramming of molecular networks associated with behavioral …

PV Tran, BC Kennedy, MT Pisansky, KJ Won… - The Journal of …, 2016 - Elsevier
Background: Early-life iron deficiency is a common nutrient deficiency worldwide. Maternal
iron deficiency increases the risk of schizophrenia and autism in the offspring. Postnatal iron …

Atypical fetal development: Fetal alcohol syndrome, nutritional deprivation, teratogens, and risk for neurodevelopmental disorders and psychopathology

MK Georgieff, PV Tran, ES Carlson - Development and …, 2018 - cambridge.org
Accumulating evidence indicates that the fetal environment plays an important role in brain
development and sets the brain on a trajectory across the life span. An abnormal fetal …

The iron status at birth of neonates with risk factors for developing iron deficiency: a pilot study

BC MacQueen, RD Christensen, DM Ward… - Journal of …, 2017 - nature.com
Objective: Small-for-gestational-age (SGA) neonates, infants of diabetic mothers (IDM) and
very-low-birth weight premature neonates (VLBW) are reported to have increased risk for …

Cord blood-derived exosomal CNTN2 and BDNF: potential molecular markers for brain health of neonates at risk for iron deficiency

PS Marell, SE Blohowiak, MD Evans, MK Georgieff… - Nutrients, 2019 - mdpi.com
Maternal iron deficiency anemia, obesity, and diabetes are prevalent during pregnancy. All
are associated with neonatal brain iron deficiency (ID) and neurodevelopmental impairment …

The impacts of maternal iron deficiency and being overweight during pregnancy on neurodevelopment of the offspring

SK Berglund, FJ Torres-Espínola… - British Journal of …, 2017 - cambridge.org
Both maternal Fe deficiency (ID) and being overweight or obese (Ow/Ob, BMI≥ 25 kg/m2)
may negatively affect offspring brain development. However, the two risk factors correlate …

The role of the dynein light intermediate chain in retrograde IFT and flagellar function in Chlamydomonas

J Reck, AM Schauer, K VanderWaal Mills… - Molecular biology of …, 2016 - Am Soc Cell Biol
The assembly of cilia and flagella depends on the activity of two microtubule motor
complexes, kinesin-2 and dynein-2/1b, but the specific functions of the different subunits are …

Helicobacter pylori Infection Induces Anemia, Depletes Serum Iron Storage, and Alters Local Iron-Related and Adult Brain Gene Expression in Male INS-GAS Mice

M Burns, S Muthupalani, Z Ge, TC Wang… - PloS one, 2015 - journals.plos.org
Iron deficiency anemia (IDA) affects> 500 million people worldwide, and is linked to
impaired cognitive development and function in children. Helicobacter pylori, a class 1 …