Tumour necrosis factor (TNF) is a classical, pleiotropic pro-inflammatory cytokine. It is also
the first 'adipokine'described to be produced from adipose tissue, regulated in obesity and …

Metabolic syndrome, a network of medical disorders that greatly increase the risk for
developing metabolic and cardiovascular diseases, has reached epidemic levels in many …

The hypothalamus is one of the master regulators of various physiological processes,
including energy balance and nutrient metabolism. These regulatory functions are mediated …

Protein tyrosine phosphatase 1B (PTP1B) is a critical negative modulator of insulin signaling
and has attracted considerable attention in treating type 2 diabetes mellitus (T2DM). Low …

Ginsenosides, the major active constituents of ginseng, have been demonstrated possess
anti-diabetic, anti-inflammatory effects. Ginsenoside Rb2 (Rb2) is the most abundant …

A obesidade atualmente é considerada uma epidemia mundial devido à relação direta com
a inflamação sistêmica, doenças cardiovasculares e metabólicas, sendo o principal fator de …

Oxidative stress damages multiple cellular components including DNA, lipids, and proteins
and has been linked to pathological alterations in nonalcoholic fatty liver disease (NAFLD) …

Patients who experience acute ischemic stroke may develop hyperglycemia, even in the
absence of diabetes. In the current study we determined the effects of acute stroke on …

Activation of Liver X receptors (LXRs), key transcriptional regulators of glucose metabolism,
normalizes glycemia and improves insulin sensitivity in rodent models with insulin …

Polysaccharide from Schisandra chinensis has the effect of lowering blood glucose and
improving insulin resistance (IR). However, its underlying mechanism remains unclear. In …