Diarrhoeal diseases collectively constitute a serious public health challenge globally,
especially as the leading cause of death in children (after respiratory diseases). Childhood …

Background Metagenomic shotgun sequencing has the potential to change how many
infections, particularly those caused by difficult-to-culture organisms, are diagnosed …

Purpose The aim of this study was to evaluate the value of metagenomic next-generation
sequencing (mNGS) in peripheral pulmonary infection management by comparing the …

This Opinion considers the application of whole genome sequencing (WGS) and
metagenomics for outbreak investigation, source attribution and risk assessment of food …

Metagenomic next-generation sequencing (mNGS) and droplet digital PCR (ddPCR) have
recently demonstrated a great potential for pathogen detection. However, few studies have …

Advances in genomics have the potential to revolutionize clinical diagnostics. Here, we
examine the microbiome of vitreous (intraocular body fluid) from patients who developed …

The rise of vancomycin-resistant Enterococcus spp.(VRE) has led to treatment challenges in
hospital settings worldwide. Hospital wastewater (HW) might disseminate this threat to the …

Introduction Bifidobacterium longum subspecies infantis (B. infantis) may play a key role in
infant gut development. This trial evaluated safety, tolerability, and efficacy of B. infantis …

Bloodstream infection (BSI) is a severe complication in immunocompromised patients. Next-
generation sequencing (NGS) allows us to analyze comprehensively and quantitatively all …

Objectives We aimed to describe the genomic epidemiology of the foodborne
gastrointestinal pathogen, Shiga toxin-producing Escherichia coli (STEC) serotype O26 …