Background The details of the functional interaction between G proteins and the G protein
coupled receptors (GPCRs) have long been subjected to extensive investigations with …

White–opaque switching in Candida albicans was first discovered in 1987. Fifteen years
later, and three years after the discovery of the mating system, it was demonstrated that the …

The availability of simple, specific, and inexpensive on-site detection methods is of key
importance for deployment of pathogen surveillance networks. We developed a …

Fungi do not have different sexes characterized by specific morphological organs but control
sexual development by physiological differences defined by mating types. While other …

Chemical gradients of peptide mating pheromones are necessary for directional growth,
which is critical for yeast mating. These gradients are generated by cell-type specific …

Engineering multicellularity is one of the next breakthroughs for Synthetic Biology. A key
bottleneck to building multicellular systems is the lack of a scalable signaling language with …

G protein-coupled receptors (GPCRs) regulate diverse biological processes in eukaryotes
and such conservation allows an almost unrestricted interchange of signalling components …

Making progress in the study of hormone‐sensitive signaling systems in vertebrates and
human requires a better understanding of how chemosignaling systems in lower eukaryotes …

The yeast α-factor receptor encoded by the STE2 gene is a member of the extended family
of G protein coupled receptors (GPCRs) involved in a wide variety of signal transduction …

Discovery of sexual development in the ascomycete Trichoderma reesei (Hypocrea
jecorina) as well as detection of a novel class of peptide pheromone precursors in this …