Epidemiology of type 2 diabetes: Indian scenario
India leads the world with largest number of diabetic subjects earning the dubious distinction
of being termed the “diabetes capital of the world”. According to the Diabetes Atlas 2006 …
of being termed the “diabetes capital of the world”. According to the Diabetes Atlas 2006 …
Lipid homeostasis, lipotoxicity and the metabolic syndrome
RH Unger, GO Clark, PE Scherer, L Orci - Biochimica et Biophysica Acta …, 2010 - Elsevier
In the 20th century industrialized nations have become afflicted with an unprecedented
pandemic of increased adiposity. In the United States, the epicenter of the epidemic, over …
pandemic of increased adiposity. In the United States, the epicenter of the epidemic, over …
The human obesity gene map: the 2005 update
T Rankinen, A Zuberi, YC Chagnon, SJ Weisnagel… - …, 2006 - Wiley Online Library
This paper presents the 12th update of the human obesity gene map, which incorporates
published results up to the end of October 2005. Evidence from single‐gene mutation …
published results up to the end of October 2005. Evidence from single‐gene mutation …
Obesity-related non-communicable diseases: South Asians vs White Caucasians
A Misra, L Khurana - International journal of obesity, 2011 - nature.com
South Asians are at higher risk than White Caucasians for the development of obesity and
obesity-related non-communicable diseases (OR-NCDs), including insulin resistance, the …
obesity-related non-communicable diseases (OR-NCDs), including insulin resistance, the …
NPP-type ectophosphodiesterases: unity in diversity
C Stefan, S Jansen, M Bollen - Trends in biochemical sciences, 2005 - cell.com
Nucleotide pyrophosphatase/phosphodiesterase (NPP)-type ectophosphodiesterases are
found at the cell surface as type-I or type-II transmembrane proteins, but are also found …
found at the cell surface as type-I or type-II transmembrane proteins, but are also found …
Smoothing proximal gradient method for general structured sparse regression
We study the problem of estimating high-dimensional regression models regularized by a
structured sparsity-inducing penalty that encodes prior structural information on either the …
structured sparsity-inducing penalty that encodes prior structural information on either the …
Autotaxin—an LPA producing enzyme with diverse functions
K Nakanaga, K Hama, J Aoki - The journal of biochemistry, 2010 - academic.oup.com
Autotaxin (ATX) is an ecto-enzyme responsible for lysophosphatidic acid (LPA) production in
blood. ATX is present in various biological fluids such as cerebrospinal and seminal fluids …
blood. ATX is present in various biological fluids such as cerebrospinal and seminal fluids …
[HTML][HTML] The genetic basis of type 2 diabetes
SK Das, SC Elbein - Cellscience, 2006 - ncbi.nlm.nih.gov
Type 2 Diabetes results from a complex physiologic process that includes the pancreatic
beta cells, peripheral glucose uptake in muscle, the secretion of multiple cytokines and …
beta cells, peripheral glucose uptake in muscle, the secretion of multiple cytokines and …
[HTML][HTML] New insights regarding genetic aspects of childhood obesity: a minireview
CO Mǎrginean, C Mǎrginean, LE Meliţ - Frontiers in pediatrics, 2018 - frontiersin.org
Introduction: Childhood obesity is occurring at alarming rates in both developed and
developing countries.“Obesogenic” environmental factors must be associated with variants …
developing countries.“Obesogenic” environmental factors must be associated with variants …
Type 2 diabetes mellitus: pathogenesis and genetic diagnosis
D Himanshu, W Ali, M Wamique - Journal of Diabetes & Metabolic …, 2020 - Springer
Type 2 diabetes mellitus (T2DM) is a heterogeneous condition that is related to both
defective insulin secretion and peripheral insulin resistance. Beta cells are the major organ …
defective insulin secretion and peripheral insulin resistance. Beta cells are the major organ …