Epidemiology of type 2 diabetes: Indian scenario

V Mohan, S Sandeep, R Deepa, B Shah… - Indian journal of …, 2007 - journals.lww.com
India leads the world with largest number of diabetic subjects earning the dubious distinction
of being termed the “diabetes capital of the world”. According to the Diabetes Atlas 2006 …

Lipid homeostasis, lipotoxicity and the metabolic syndrome

RH Unger, GO Clark, PE Scherer, L Orci - Biochimica et Biophysica Acta …, 2010 - Elsevier
In the 20th century industrialized nations have become afflicted with an unprecedented
pandemic of increased adiposity. In the United States, the epicenter of the epidemic, over …

The human obesity gene map: the 2005 update

T Rankinen, A Zuberi, YC Chagnon, SJ Weisnagel… - …, 2006 - Wiley Online Library
This paper presents the 12th update of the human obesity gene map, which incorporates
published results up to the end of October 2005. Evidence from single‐gene mutation …

Obesity-related non-communicable diseases: South Asians vs White Caucasians

A Misra, L Khurana - International journal of obesity, 2011 - nature.com
South Asians are at higher risk than White Caucasians for the development of obesity and
obesity-related non-communicable diseases (OR-NCDs), including insulin resistance, the …

NPP-type ectophosphodiesterases: unity in diversity

C Stefan, S Jansen, M Bollen - Trends in biochemical sciences, 2005 - cell.com
Nucleotide pyrophosphatase/phosphodiesterase (NPP)-type ectophosphodiesterases are
found at the cell surface as type-I or type-II transmembrane proteins, but are also found …

Smoothing proximal gradient method for general structured sparse regression

X Chen, Q Lin, S Kim, JG Carbonell, EP Xing - 2012 - projecteuclid.org
We study the problem of estimating high-dimensional regression models regularized by a
structured sparsity-inducing penalty that encodes prior structural information on either the …

Autotaxin—an LPA producing enzyme with diverse functions

K Nakanaga, K Hama, J Aoki - The journal of biochemistry, 2010 - academic.oup.com
Autotaxin (ATX) is an ecto-enzyme responsible for lysophosphatidic acid (LPA) production in
blood. ATX is present in various biological fluids such as cerebrospinal and seminal fluids …

[HTML][HTML] The genetic basis of type 2 diabetes

SK Das, SC Elbein - Cellscience, 2006 - ncbi.nlm.nih.gov
Type 2 Diabetes results from a complex physiologic process that includes the pancreatic
beta cells, peripheral glucose uptake in muscle, the secretion of multiple cytokines and …

[HTML][HTML] New insights regarding genetic aspects of childhood obesity: a minireview

CO Mǎrginean, C Mǎrginean, LE Meliţ - Frontiers in pediatrics, 2018 - frontiersin.org
Introduction: Childhood obesity is occurring at alarming rates in both developed and
developing countries.“Obesogenic” environmental factors must be associated with variants …

Type 2 diabetes mellitus: pathogenesis and genetic diagnosis

D Himanshu, W Ali, M Wamique - Journal of Diabetes & Metabolic …, 2020 - Springer
Type 2 diabetes mellitus (T2DM) is a heterogeneous condition that is related to both
defective insulin secretion and peripheral insulin resistance. Beta cells are the major organ …