[HTML][HTML] Pathological sequelae of long-haul COVID
S Mehandru, M Merad - Nature immunology, 2022 - nature.com
The world continues to contend with successive waves of coronavirus disease 2019 (COVID-
19), fueled by the emergence of viral variants. At the same time, persistent, prolonged and …
19), fueled by the emergence of viral variants. At the same time, persistent, prolonged and …
[HTML][HTML] Endothelial dysfunction and immunothrombosis as key pathogenic mechanisms in COVID-19
A Bonaventura, A Vecchié, L Dagna… - Nature Reviews …, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) is a clinical syndrome caused by infection
with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients with severe …
with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients with severe …
[HTML][HTML] Community transmission and viral load kinetics of the SARS-CoV-2 delta (B. 1.617. 2) variant in vaccinated and unvaccinated individuals in the UK: a …
A Singanayagam, S Hakki, J Dunning… - The lancet infectious …, 2022 - Elsevier
Summary Background The SARS-CoV-2 delta (B. 1.617. 2) variant is highly transmissible
and spreading globally, including in populations with high vaccination rates. We aimed to …
and spreading globally, including in populations with high vaccination rates. We aimed to …
[HTML][HTML] Viral infection and transmission in a large, well-traced outbreak caused by the SARS-CoV-2 Delta variant
B Li, A Deng, K Li, Y Hu, Z Li, Y Shi, Q Xiong… - Nature …, 2022 - nature.com
Abstract The SARS-CoV-2 Delta variant has spread rapidly worldwide. To provide data on
its virological profile, we here report the first local transmission of Delta in mainland China …
its virological profile, we here report the first local transmission of Delta in mainland China …
[HTML][HTML] Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults
B Killingley, AJ Mann, M Kalinova, A Boyers… - Nature Medicine, 2022 - nature.com
Since its emergence in 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) has caused hundreds of millions of cases and continues to circulate globally. To establish …
2) has caused hundreds of millions of cases and continues to circulate globally. To establish …
[HTML][HTML] Infectious viral load in unvaccinated and vaccinated individuals infected with ancestral, Delta or Omicron SARS-CoV-2
O Puhach, K Adea, N Hulo, P Sattonnet, C Genecand… - Nature Medicine, 2022 - nature.com
Infectious viral load (VL) expelled as droplets and aerosols by infected individuals partly
determines transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
determines transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
Estimating infectiousness throughout SARS-CoV-2 infection course
INTRODUCTION Although post facto studies have revealed the importance of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission from presymptomatic …
respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission from presymptomatic …
[HTML][HTML] COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets
COVID-19, which is caused by SARS-CoV-2, can result in acute respiratory distress
syndrome and multiple organ failure–, but little is known about its pathophysiology. Here we …
syndrome and multiple organ failure–, but little is known about its pathophysiology. Here we …
[HTML][HTML] CRISPR-based diagnostics
MM Kaminski, OO Abudayyeh, JS Gootenberg… - Nature Biomedical …, 2021 - nature.com
The accurate and timely diagnosis of disease is a prerequisite for efficient therapeutic
intervention and epidemiological surveillance. Diagnostics based on the detection of nucleic …
intervention and epidemiological surveillance. Diagnostics based on the detection of nucleic …
[HTML][HTML] Adaptive immunity to SARS-CoV-2 and COVID-19
The adaptive immune system is important for control of most viral infections. The three
fundamental components of the adaptive immune system are B cells (the source of …
fundamental components of the adaptive immune system are B cells (the source of …