Strategic design and fabrication of engineered scaffolds for articular cartilage repair
Damage to articular cartilage can eventually lead to osteoarthritis (OA), a debilitating,
degenerative joint disease that affects millions of people around the world. The limited …
degenerative joint disease that affects millions of people around the world. The limited …
Cartilage biomechanics: From the basic facts to the challenges of tissue engineering
Articular cartilage (AC) is the thin tissue that covers the long bone ends in the joints and that
ensures the transmission of forces between adjacent bones while allowing nearly …
ensures the transmission of forces between adjacent bones while allowing nearly …
3D Bioprinting of osteochondral tissue substitutes – in vitro-chondrogenesis in multi-layered mineralized constructs
For the generation of multi-layered full thickness osteochondral tissue substitutes with an
individual geometry based on clinical imaging data, combined extrusion-based 3D printing …
individual geometry based on clinical imaging data, combined extrusion-based 3D printing …
Nanocellulose-based interpenetrating polymer network (IPN) hydrogels for cartilage applications
Double cross-linked interpenetrating polymer network (IPN) hydrogels of sodium alginate
and gelatin (SA/G) reinforced with 50 wt% cellulose nanocrystals (CNC) have been …
and gelatin (SA/G) reinforced with 50 wt% cellulose nanocrystals (CNC) have been …
3D fiber-deposited scaffolds for tissue engineering: influence of pores geometry and architecture on dynamic mechanical properties
One of the main issues in tissue engineering is the fabrication of scaffolds that closely mimic
the biomechanical properties of the tissues to be regenerated. Conventional fabrication …
the biomechanical properties of the tissues to be regenerated. Conventional fabrication …
Fibril reinforced poroelastic model predicts specifically mechanical behavior of normal, proteoglycan depleted and collagen degraded articular cartilage
RK Korhonen, MS Laasanen, J Töyräs… - Journal of …, 2003 - Elsevier
Degradation of collagen network and proteoglycan (PG) macromolecules are signs of
articular cartilage degeneration. These changes impair cartilage mechanical function …
articular cartilage degeneration. These changes impair cartilage mechanical function …
Zone-dependent mechanical properties of human articular cartilage obtained by indentation measurements
J Antons, MGM Marascio, J Nohava, R Martin… - Journal of Materials …, 2018 - Springer
Emerging 3D printing technology permits innovative approaches to manufacture cartilage
scaffolds associated with layer-by-layer mechanical property adaptation. However …
scaffolds associated with layer-by-layer mechanical property adaptation. However …
High strength astringent hydrogels using protein as the building block for physically cross-linked multi-network
Integrating proteins into a hydrogel network enables its good bioactivity as an ECM
environment in biorelative applications. Although extensive studies on preparing protein …
environment in biorelative applications. Although extensive studies on preparing protein …
[HTML][HTML] Tough hydrogels for soft artificial muscles
Mimicking the natural actuating systems artificially provides ample opportunities in the field
of soft robotics. In this domain, recent advancements in tough hydrogels along with …
of soft robotics. In this domain, recent advancements in tough hydrogels along with …
International Cartilage Repair Society (ICRS) recommended guidelines for histological endpoints for cartilage repair studies in animal models and clinical trials
Cartilage repair strategies aim to resurface a lesion with osteochondral tissue resembling
native cartilage, but a variety of repair tissues are usually observed. Histology is an …
native cartilage, but a variety of repair tissues are usually observed. Histology is an …