Anti-inflammatory agents as modulators of the inflammation in adipose tissue: A systematic review

SS da Cruz Nascimento, JL Carvalho de Queiroz… - PLoS …, 2022 - journals.plos.org
Obesity is characterized by an adipose tissue mass expansion that presents a risk to health,
associated with a chronic increase in circulating inflammatory mediators. Anti-inflammatory …

[HTML][HTML] The role of patient preferences in adherence to treatment in chronic disease: a narrative review

S Losi, CCF Berra, R Fornengo, D Pitocco… - Drug target …, 2021 - ncbi.nlm.nih.gov
Adherence to prescribed medication is important to the management of all diseases,
especially those of chronic nature. Drug effectiveness is substantially compromised by …

Tamarind trypsin inhibitor in chitosan–whey protein nanoparticles reduces fasting blood glucose levels without compromising insulinemia: A preclinical study

LLR Matias, ROA Costa, TS Passos, JLC Queiroz… - Nutrients, 2019 - mdpi.com
In vivo studies show the benefits of the trypsin inhibitor isolated from tamarind
(Tamarindusindica L.)(TTI) seeds in satiety and obesity. In the present study, TTI …

An Insulin Receptor-Binding Multifunctional Protein from Tamarindus indica L. Presents a Hypoglycemic Effect in a Diet-Induced Type 2 Diabetes—Preclinical Study

I Costa, M Lima, A Medeiros, L Bezerra, P Santos… - Foods, 2022 - mdpi.com
The objectives of this study were to evaluate the hypoglycemic effect of the trypsin inhibitor
isolated from tamarind seeds (TTI) in an experimental model of T2DM and the in silico …

Structural insights and molecular dynamics into the inhibitory mechanism of a Kunitz-type trypsin inhibitor from Tamarindus indica L

AF de Medeiros, BBP de Souza… - Journal of Enzyme …, 2021 - Taylor & Francis
Trypsin inhibitors from tamarind seed have been studied in vitro and in preclinical studies for
the treatment of obesity, its complications and associated comorbidities. It is still necessary …

[HTML][HTML] Safety and potential functionality of nanoparticles loaded with a trypsin inhibitor isolated from tamarind seeds

RO de Araújo Costa, LLR Matias, TS Passos… - Future Foods, 2020 - Elsevier
The trypsin inhibitor isolated from tamarind seeds (TTI) presents satietogenic and anti-
inflammatory effects. In the present study, TTI encapsulation by nanoprecipitation in purified …

Beneficial effects of tamarind trypsin inhibitor in chitosan–whey protein nanoparticles on hepatic injury induced high glycemic index diet: a preclinical study

AJFC Aguiar, JLC de Queiroz, PPA Santos… - International Journal of …, 2021 - mdpi.com
Several studies have sought new therapies for obesity and liver diseases. This study
investigated the effect of the trypsin inhibitor isolated from tamarind seeds (TTI) …

[HTML][HTML] Tamarind multifunctional protein: Safety and anti-inflammatory potential in intestinal mucosa and adipose tissue in a preclinical model of diet-induced obesity

VCO Lima, A Luz, MSM Amarante, MCJS Lima… - Obesity Facts, 2021 - karger.com
Introduction: Obesity has emerged as one of the main public health problems. This condition
triggers a series of hormonal and metabolic changes related to a low-grade chronic …

Antibacterial action mechanisms and mode of trypsin inhibitors: a systematic review

AM de Souza Nascimento… - Journal of Enzyme …, 2022 - Taylor & Francis
This systematic review (SR) aimed to gather studies describing the antibacterial action
mechanisms and mode of trypsin inhibitors. The review protocol was registered …

Prospecting in silico antibacterial activity of a peptide from trypsin inhibitor isolated from tamarind seed

GS Oliveira, AMS Nascimento, ABS Luz… - Journal of Enzyme …, 2023 - Taylor & Francis
Bacterial infections have become a global concern, stimulating the growing demand for
natural and biologically safe therapeutic agents with antibacterial action. This study was …